Part of the Springer Theses book series (Springer Theses)
Thielocin B1 has been identified as a protein–protein interaction (PPI) inhibitor of proteasome-assembling chaperone 3 (PAC3), and the first total synthesis of thielocin B1 and its spin-labeled derivative have been described in detail.
KeywordsDiphenyl Ether Total Synthesis Paramagnetic Relaxation Enhancement Chemical Shift Perturbation Lactone Moiety
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