Abstract
Histopathologic features of ovarian clear cell carcinoma (CCC) which are not in themselves diagnostic but are very common include the presence of oxyphil cells (prominent in 25–30 % of cases) and of endometriosis (found in the tumor-bearing ovary in 43 % of our cases, in most of which a direct origin of CCC could be demonstrated). The endometriosis was at least focally atypical in 69 % of the cases. Other findings in ovarian CCC which were either less specific and/or less common included signet ring cells, stromal inflammatory infiltrates/necrosis/cholesterol clefts/fibrosis, stromal edema or mucinous material, clefts around tumor cell nests, tumor multinodularity, thanatosomes, and foci of calcification with or without psammoma bodies and rarely ossification.
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Kigawa, J., Kaku, T., Sugiyama, T., Silverberg, S.G. (2015). Histopathologic Variations. In: Atlas of Clear Cell Carcinoma of the Ovary. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55438-7_4
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DOI: https://doi.org/10.1007/978-4-431-55438-7_4
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-55437-0
Online ISBN: 978-4-431-55438-7
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