Abstract
Modern imaging techniques including computed tomography, magnetic resonance imaging, and ultrasonography have advanced greatly over the last three decades, allowing the causes of vocal fold paralysis (VFP) to be established and improving the surgical treatment of patients with previously inoperable life-threatening diseases. However, VFP sometimes persists or even appears as a complication following surgery, resulting in breathy dysphonia and/or swallowing difficulties that affect postoperative quality of life (QOL) [1–4]. Thus, phonosurgical treatment of patients with paralytic dysphonia is important to improve QOL after treatment of the primary disease. In this chapter, the author reviews his experience in terms of the etiologies of VFP, the optimal surgical treatments for breathy dysphonia, and the vocal outcomes after surgery.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Smith E, Taylor M, Mendoza M, Barkmeier J, Lemke J, Hoffman H. Spasmodic dysphonia and vocal fold paralysis: outcomes of voice problems on work-related functioning. J Voice. 1998;12:223–32.
Benninger MS, Ahuja AS, Gardner G, Grywalski C. Assessing outcomes for dysphonic patients. J Voice. 1998;12:540–50.
Baba M, Natsugoe S, Shimada M, Nakano S, Noguchi Y, Kawachi K, Kusano C, Aikou T. Does hoarseness of voice from recurrent nerve paralysis after esophagectomy for carcinoma influence patient quality of life? J Am Coll Surg. 1999;188:231–6.
Fang TJ, Li HY, Glicklich RE, Chen YH, Wang PC, Chuang HF. Quality of life measures and predictors for adults with unilateral vocal cord paralysis. Laryngoscope. 2008;118:1837–41.
Bachor E, Bonkowsky V, Hacki T. Herpes simplex virus type I reactivation as a cause of a unilateral temporary paralysis of the vagus nerve. Eur Arch Otorhinolaryngol. 1996;253:297–300.
Amin MR, Koufman JA. Vagal neuropathy after upper respiratory infection: a viral etiology? Am J Otolaryngol. 2001;22:251–6.
Pinto JA, Pinto HCF, Ramalho JRO. Laryngeal herpes: a case report. J Voice. 2002;16:560–3.
Nakagawa H, Satoh M, Kusuyama T, Fukuda H, Ogawa K. Isolated vagus nerve paralysis caused by varicella zoster virus reactivation. Otolaryngol Head Neck Surg. 2005;133:460–1.
Chitose S, Umeno H, Hamakawa S, Nakashima T, Shoji H. Unilateral associated laryngeal paralysis due to varicella-zoster virus: virus antibody testing and videofluoroscopic findings. J Laryngol Otol. 2008;122:170–6.
Lin YY, Kao CH, Wang CH. Varicella zoster virus infection of the pharynx and larynx with multiple cranial neuropathies. Laryngoscope. 2011;121:1627–30.
Brunings W. Uber eine neue Behandlungsmethode der Rekurrenslamung. Verhandl ver Deutsch Laryngol. 1911;18:93–151.
Arnold GE. Alleviation of aphonia or dysphonia through intracordal injection of Teflon paste. Ann Otol Rhinol Laryngol. 1963;72:384–95.
Arnold GE. Further experiences with intracordal Teflon injection. Laryngoscope. 1964;74:802–15.
Ward PH. Use of injectable Teflon in otolaryngology. Arch Otolaryngol. 1968;87:637–43.
Donnellan WL, Gabriel W, Maurizi DG, et al. The use of silastic in the treatment of unilateral cord paralysis. An experimental study. Ann Otol Rhinol Laryngol. 1966;75:646–56.
Fukuda H. Vocal rehabilitation by silicon injection. Nippon Jibiinkouka Gakkai Kaiho. 1970;73:1506–26. (in Japanese)
Lewy RB. Teflon injection of the vocal cord: complications, errors, and precautions. Ann Otol Rhinol Laryngol. 1983;92:473–4.
Varvares MA, Montgomery WW, Hilman RE. Teflon granuloma of the larynx: etiology, pathophysiology, and management. Ann Otol Rhinol Laryngol. 1995;104:511–5.
Flint PW, Corio RL, Cummings CW. Comparison of soft tissue response in rabbits following laryngeal implantation with hydroxylapatite, silicone rubber, and Teflon. Ann Otol Rhinol Laryngol. 1997;106:399–407.
Andrews JM. Cellular behavior to injected silicone fluid: a preliminary report. Plast Reconstr Surg. 1966;38:581–3.
Tsuzuki T, Fukuda H, Fujioka T. Response of the human larynx to silicone. Am J Otolaryngol. 1991;12:288–91.
Ford CH, Bless DM. A preliminary study of injectable collagen in human vocal fold augmentation. Otolaryngol Head Neck Surg. 1986;94:104–22.
Mikaelian D, Lowry LD, Sataloff RT. Lipoinjection for unilateral vocal cord paralysis. Laryngoscope. 1991;101:465–9.
Laccourreye O, Papon JF, Kania R, et al. Intracordal injection of autologous fat in patients with unilateral laryngeal nerve paralysis: long-term results from the patient’s perspective. Laryngoscope. 2003;113:541–5.
Rihkanen H. Vocal fold augmentation by injection of autologous fascia. Laryngoscope. 1998;108:51–4.
Duke SG, Salmon J, Blalock D, Postma GN, Koufman JA. Fascia augmentation of the vocal fold: graft yield in the canine and preliminary clinical experience. Laryngoscope. 2001;111:759–64.
Karpenko A, Dworkin J, Meleca R, et al. Cymetra injection for unilateral vocal fold paralysis. Ann Otol Rhinol Laryngol. 2003;112:927–34.
Milstein CF, Akst LM, Hicks D, Abelson TI, Strome M. Long-term effects of micronized AlloDerm injection for unilateral vocal fold paralysis. Laryngoscope. 2005;115:1691–6.
Belafsky PC, Postma GN. Vocal fold augmentation with calcium hydroxylapatite. Otolaryngol Head Neck Surg. 2004;131:351–4.
Carrol TL, Rosen CA. Long-term results of calcium hydroxylapatite for vocal fold augmentation. Laryngoscope. 2011;121:313–9.
Gillespie MB, Dozier TS, Day TA, Martin-Harris B, Nguyen SA. Effectiveness of hydroxylapatite paste in vocal rehabilitation. Ann Otol Rhinol Laryngol. 2009;118:546–51.
Finck C, Lefebvre P. Implantation of esterified hyaluronic acid in microdissected Reinke’s space after vocal fold microsurgery: first clinical experiences. Laryngoscope. 2005;115:1841–7.
Upton DC, Johnson M, Zelazny SK, Dailey SH. Prospective evaluation of office-based injection laryngoplasty with hyaluronic acid gel. Ann Otol Rhinol Laryngol. 2013;122:541–6.
Sato K, Umeno H, Nakashima T. Autologous fat injection laryngopharyngoplasty for aspiration after vocal fold paralysis. Ann Otol Rhinol Laryngol. 2004;113:87–92.
Tamura E, Fukuda H, Tabata Y, Nishimura M. Use of the buccal fat pad for vocal cord augmentation. Acta Otolaryngol. 2008;128:219–24.
Tamura E, Fukuda H, Tabata Y. Adipose tissue formation in response to basic fibroblast growth factor. Acta Otolaryngol. 2007;127:1327–31.
Mikus JL, Koufman JA, Kilpatrick SE. Fate of liposuctioned and purified autologous fat injections in the canine vocal fold. Laryngoscope. 1995;105:17–22.
Bauer CA, Valentino J, Hoffman HT. Long-term result of vocal cord augmentation with autogenous fat. Ann Otol Rhinol Laryngol. 1995;104:871–4.
Cantarella G, Mazzola RF, Domenichini E, Arnone F, Maraschi B. Vocal fold augmentation by autologous fat injection with lipostructure procedure. Otolaryngol Head Neck Surg. 2005;132:239–43.
Tamura E, Okada S, Shibuya M, Iida M. Comparison of fat tissues used in intrcordal autologous fat injection. Acta Otolaryngol. 2010;130:405–9.
Tsunoda K, Takanosawa M, Niimi S. Autologous transplantation of fascia into the vocal fold: a new phonosurgical technique for glottal incompetence. Laryngoscope. 1999;109:504–8.
Tsunoda K, Niimi S. Autologous transplantation of fascia into the vocal fold. Laryngoscope. 2000;110:680–2.
Tsunoda K, Baer T, Niimi S. Autologous transplantation of fascia into the vocal fold: long-term results of a new phonosurgical technique for glottal incompetence. Laryngoscope. 2001;111:453–7.
Nishiyama K, Hirose H, Iguchi Y, Nagai H, Yamanaka J, Okamoto M. Autologous transplantation of fascia into the vocal fold as a treatment for recurrent nerve paralysis. Laryngoscope. 2002;112:1420–5.
Nishiyama K, Hirose H, Masaki T, Nagai H, Hashimoto D, Usui D, Yao K, Tsunoda K, Okamoto M. Long-term result of the new endoscopic vocal fold medialization surgical technique for laryngeal palsy. Laryngoscope. 2006;116:231–4.
Sulica L, Rosen CA, Postma GN, Simpson B, Amin M, Courey M, Merati A. Current practice in injection augmentation of the vocal folds: indications, treatment principles, techniques, and complications. Laryngoscope. 2010;120:319–25.
Payr E. Plastik am Schildknorpel zur Behebung der Folgen einseitiger Stimmbandlahmung. Dtsch Med Wochenschr. 1915;43:1265–70.
Meurmann Y. Operative mediofixation of the vocal cord in complete unilateral paralysis. Arch Otolaryngol. 1952;55:544–53.
Opheim O. Unilateral paralysis of the vocal cord. Acta Otolaryngol. 1955;45:226–30.
Sawashima M, Totsuka G, Kobayashi T, Hirose H. Surgery for hoarseness due to unilateral vocal cord paralysis. Arch Otolaryngol. 1968;87:289–94.
Bernstein L, Holt GP. Correction of vocal cord abduction in unilateral recurrent laryngeal nerve paralysis by transposition of the sternohyoid muscle. An experimental study in dogs. Laryngoscope. 1967;77:876–85.
Isshiki N, Morita H, Okamura H, Hiramoto M. Thyroplasty as a new phonosurgical technique. Acta Otolaryngol. 1974;78:451–7.
Isshiki N, Okamura H, Ishikawa T. Thyroplasty type I (lateral compression) for dysphonia due to vocal cord paralysis or atrophy. Acta Otolaryngol. 1975;80:465–73.
Carrau RL, Myers EN. Localization of true vocal cord for medialization thyroplasty. Laryngoscope. 1995;105:534–6.
Lee EC, Kuriloff DB. The pilot hole technique in type I thyroplasty. Laryngoscope. 1995;105:768–70.
Cummings CW, Purcell LL, Flint PW. Hydroxylapatite laryngeal implants for medialization: preliminary report. Ann Otol Rhinol Laryngol. 1993;102:843–51.
Montgomery WW, Montgomery SK. Montgomery thyroplasty implant system. Ann Otol Rhinol Laryngol. 1997;170(Suppl):1–16.
Friedrich G. Titanium vocal fold medialization implant: Introducing a novel implant system for external vocal fold medialization. Ann Otol Rhinol Laryngol. 1999;108:79–86.
McCulloch TM, Hoffman HT. Medialization laryngoplasty with expanded polytetrafluoroethylene. Surgical technique and preliminary results. Ann Otol Rhinol Laryngol. 1998;107:427–32.
Morrison LF. The “Reverse King operation”. Ann Otol Rhinol Laryngol. 1948;57:945–56.
Montgomery WW. Cricoarytenoid arthrodesis. Ann Otol Rhinol Laryngol. 1966;75:380–91.
Isshiki N, Tanabe M, Sawada M. Arytenoid adduction for unilateral vocal cord paralysis. Arch Otolaryngol. 1978;104:555–8.
Iwamura S, Kurita N. A new arytenoid adduction technique for one-vocal-fold paralysis-a direct pull of the lateral cricoarytenoid muscle. Tokeibugeka. 1996;6:1–10. (in Japanese)
Sonoda S, Kataoka H, Inoue T. Traction of lateral cricoarytenoid muscle for unilateral vocal fold paralysis: comparison with Isshiki’s original technique of arytenoids adduction. Ann Otol Rhinol Laryngol. 2005;114:132–8.
Tokashiki R, Hiramatsu H, Tsukahara K, Kanebayashi H, Nakamura M, Motohashi R, Yamada T, Suzuki M. A “fenestration approach” for arytenoid adduction through the thyroid ala combined with type I thyroplasty. Laryngoscope. 2007;117:1882–92.
Maragos NE. The posterior thyroplasty window: anatomical considerations. Laryngoscope. 1999;109:1228–31.
Su CY, Lui CC, Lin HC, Chiu JF, Cheng CA. A new paramedian approach to arytenoid adduction and strap muscle transposition for vocal fold medialization. Laryngoscope. 2002;112:342–50.
Slavit DH, Maragos NE. Physiologic assessment of arytenoid adduction. Ann Otol Rhinol Laryngol. 1992;101:321–7.
Su CY, Tsai SS, Chuang HCC, Chiu JF. Functional significance of arytenoid adduction with the suture attaching to cricoid cartilage versus to thyroid cartilage for unilateral paralytic dysphonia. Laryngoscope. 2005;115:1752–9.
Woodson GE, Picerno R, Yeung D, Hengesteg A. Arytenoid adduction: controlling vertical position. Ann Otol Rhinol Laryngol. 2000;109:360–4.
Rosen CA. Complications of phonosurgery: results of a national survey. Laryngoscope. 1998;108:1697–703.
Weinman EC, Maragos NE. Airway compromise in thyroplastic surgery. Laryngoscope. 2000;110:1082–5.
Abraham MT, Gonen M, Kraus DH. Complications of type I thyroplasty and arytenoids adduction. Laryngoscope. 2001;111:1322–9.
Maragos N. Pyriform sinus mucosa stabilization for prevention of postoperative airway obstruction in arytenoids adduction. Ann Otol Rhinol Laryngol. 2006;115:171–4.
Yumoto E, Nakano K, Oyamada Y, Hyodo M, Kobayashi J, Sanuki T. Laryngeal framework surgery for patients with unilateral vocal fold paralysis–present status and issues for future development. Tokeibugeka. 2001;11:83–9. (in Japanese)
Kraus DH, Orlikoff RF, Rizk SS, Rosenberg DB. Arytenoid adduction as an adjunct to type I thyroplasty for unilateral vocal cord paralysis. Head Neck. 1999;21:52–9.
McCulloch TM, Hoffman HT, Andrews BT, Karnell MP. Arytenoid adduction combined with Gore-tex medialization thyroplasty. Laryngoscope. 2000;110:1306–11.
Mortensen M, Carroll L, Woo P. Arytenoid adduction with medialization laryngoplasty versus injection or medialization laryngoplasty: the role of the arytenoidopexy. Laryngoscope. 2009;119:827–31.
Kimura M, Nito T, Imagawa H, Tayama N, Chan RW. Collagen injection as a supplement to arytenoid adduction for vocal fold paralysis. Ann Otol Rhinol Laryngol. 2008;117:430–6.
Zeitels SM, Hochman IH, Hillman RE. Adduction arytenopexy: a new procedure for paralytic dysphonia with implications for implant medialization. Ann Otol Rhinol Laryngol. 1998;107 Suppl 173:2–24.
Zeitels SM, Mauri M, Dailey SH. Adduction arytenopexy for vocal fold paralysis: indications and technique. J Laryngol Otol. 2004;118:508–16.
Zeitels SM, Hillman RE, Desloge RB, Bunting GA. Cricothyroid subluxation: a new innovation for enhancing the voice with laryngoplastic phonosurgery. Ann Otol Rhinol Laryngol. 1999;108:1126–31.
Haji T, Omori K, Mori K, Kojima H, Taira T, Isshiki N. Phonation after thyroplasty and arytenoid adduction. Pract Otorhinolaryngol. 1990;83:915–22. (in Japanese)
Isshiki N. Phonosurgery: theory and practice. Tokyo: Springer; 1989.
Nonomura M, Kojima H, Omori K, Kanaji M, Honjo I, Nakamura T, Shimizu Y. Remobilization of paralyzed vocal cord by anticus-lateralis muscle suturing. Arch Otolaryngol Head Neck Surg. 1993;119:498–503.
Nonomura M, Kojima H, Omori K, Ishijima K, Hirano S, Hopnjo I. Dynamic reconstruction for unilateral recurrent laryngeal nerve paralysis: clinical application of anticus-lateralis muscle suturing. Pract Otorhinolaryngol. 1992;85:1095–100.
Miyauchi A, Matsusaka K, Kihara M, Matsuzuka F, Hirai K, Yokozawa T, Kobayashi A, Kuma K. The role of ansa-to-recurrent laryngeal nerve anastomosis in operations for thyroid cancer. Eur J Surg. 1998;164:927–33.
Miyauchi A, Inoue H, Tomoda C, Fukushima M, Kihara M, Higashiyama T, Takamura Y, Ito Y, Kobayashi K, Miya A. Improvement in phonation after reconstruction of the recurrent laryngeal nerve in patients with thyroid cancer invading the nerve. Surgery. 2009;146:1056–62.
Yumoto E, Sanuki T, Kumai Y. Immediate recurrent laryngeal nerve reconstruction and vocal outcome. Laryngoscope. 2006;116:1657–61.
Sanuki T, Yumoto E, Minoda R, Kodama N. The role of immediate recurrent laryngeal nerve reconstruction for thyroid cancer surgery. J Oncol. 2010;846235.
Yumoto E, Gould J, Baer T. Harmonics-to-noise ratio as an index of the degree of hoarseness. J Acoust Soc Am. 1982;71:1544–50.
Tanaka S, Asato T, Hiratsuka Y. Nerve-muscle transplantation to the paraglottic space after resection of recurrent laryngeal nerve. Laryngoscope. 2004;114:1118–22.
Tucker HM. Reinnervation of the unilaterally paralyzed larynx. Ann Otol Rhinol Laryngol. 1977;86:789–94.
Tucker HM, Rusnov M. Laryngeal reinnervation for unilateral vocal cord paralysis: long-term results. Ann Otol Rhinol Laryngol. 1981;90:457–9.
Tucker HM. Combined laryngeal framework medicalization and reinnervation for unilateral vocal fold paralysis. Ann Otol Rhinol Laryngol. 1990;99:778–81.
Tucker HM. Combined surgical medicalization and nerve-muscle pedicle reinnervation for unilateral vocal fold paralysis: improved functional results and prevention of long-term deterioration of voice. J Voice. 1997;11:474–8.
Tucker HM. Long-term preservation of voice improvement following surgical medicalization and reinnervation for unilateral vocal fold paralysis. J Voice. 1999;13:251–6.
May M, Beery Q. Muscle-nerve pedicle laryngeal reinnervation. Laryngoscope. 1986;96:1196–200.
Maronian N, Waugh P, Robinson L, Hillel A. Electromyographic findings in recurrent laryngeal nerve reinnervation. Ann Otol Rhinol Laryngol. 2003;112:314–23.
Crumley RL, Izdebski K. Voice quality following laryngeal reinnervation by ansa hypoglossi transfer. Laryngoscope. 1986;96:611–6.
Crumley RL, Izdebski K, McMicken B. Nerve transfer versus Teflon injection for vocal cord paralysis: a comparison. Laryngoscope. 1988;98:1200–4.
Crumley RL. Update: ansa cervicalis to recurrent laryngeal nerve anastomosis for unilateral laryngeal paralysis. Laryngoscope. 1991;101:384–8.
Lorenz RR, Esclamado RM, Teker AM, Strome M, Scharpf J, Hicks D, Milstein C, Lee WT. Ansa cervicalis-to-recurrent laryngeal nerve anastomosis for unilateral vocal fold paralysis: experience of a single institution. Ann Otol Rhinol Laryngol. 2008;117:40–5.
Olson DL, Goding GS, Michael DD. Acoustic and perceptual evaluation of laryngeal reinnervation by ansa cervicalis transfer. Laryngoscope. 1998;108:1767–72.
Paniello RC. Laryngeal reinnervation with the hypoglossal nerve: II. Clinical evaluation and early patient experience. Laryngoscope. 2000;110:739–48.
Su WF, Hsu YD, Chen HC, Sheng H. Laryngeal reinnervation by ansa cervicalis nerve implantation for unilateral vocal cord paralysis in humans. J Am Coll Surg. 2007;204:64–72.
Paniello RC, Edgar JD, Kallogjeri D, Piccirillo JF. Medialization versus reinnervation for unilateral vocal fold paralysis: a multicenter randomized clinical trial. Laryngoscope. 2011;121:2172–9.
Chhetri DK, Gerratt BR, Kreinman J, Berke GS. Combined arytenoid adduction and laryngeal reinnervation in the treatment of vocal fold paralysis. Laryngoscope. 1999;109:1928–36.
Hassan MM, Yumoto E, Kumai Y, Sanuki T, Kodama N. Vocal outcome after arytenoid adduction and ansa cervicalis transfer. Aech Otolaryngol Head Neck Surg. 2012;138:60–5.
Shaw GY, Szewczyk MA, Searle J, Woodroof J. Autologous fat injection into the vocal folds: technical considerations and long-term follow-up. Laryngoscope. 1997;107:177–86.
McCulloch TM, Andrews BT, Hoffman HT, Graham SM, Karnell MP, Minnick C. Long-term follow-up of fat injection laryngoplasty for unilateral vocal cord paralysis. Laryngoscope. 2002;112:1235–8.
Reijonen P, Lehikoinen-Sodeerlund S, Rihkanen H. Results of fascial augmentation in unilateral vocal fold paralysis. Ann Otol Rhinol Laryngol. 2002;111:523–9.
Cheng Y, Li Z, Huang J, Xue F, Jiang M, Wu K, Wang Q. Combination of autologous fascia lata and fat injection into the vocal fold via the cricothyroid gap for unilateral vocal fold paralysis. Arch Otolaryngol Head Neck Surg. 2009;135:759–63.
Lu FL, Casiano RR, Lundy DS, Xue JW. Longitudinal evaluation of vocal function after thyroplasty type I in the treatment of unilateral vocal paralysis. Laryngoscope. 1996;106:573–7.
Suehiro A, Hirano M, Kishimoto Y, Tanaka S, Ford CN. Comparative study of vocal outcomes with silicone versus Gore-tex thyroplasty. Ann Otol Rhinol Laryngol. 2009;118:405–8.
Yumoto E, Okamoto K, Kawamura Y, Okamura H. Injection of atelocollagen to augment the paralyzed vocal fold. J Jpn Bronchoesophagol Soc. 1988;39:271–4. (in Japanese)
Yumoto E, Kadota Y. Thyroplasty type I as the treatment of hoarseness due to unilateral recurrent laryngeal nerve palsy. J Jpn Soc Head Neck Surg. 1993;3:161–7. (in Japanese)
Hyodo M, Yumoto E, Mori T, Kadota Y. Postoperative evaluation after arytenoid adduction. Practica Oto-Rhino-Laryngol. 1997;90:1129–34. (in Japanese)
Yumoto E, Oyamada Y, Goto H. Recent modifications in arytenoid adduction combined with type I thyroplasty. Larynx Jpn. 2003;15:78–83. (in Japanese)
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer Japan
About this chapter
Cite this chapter
Yumoto, E. (2015). Etiologies of Vocal Fold Paralysis and Conventional Surgical Procedures Used to Treat Paralytic Dysphonia. In: Pathophysiology and Surgical Treatment of Unilateral Vocal Fold Paralysis. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55354-0_2
Download citation
DOI: https://doi.org/10.1007/978-4-431-55354-0_2
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-55353-3
Online ISBN: 978-4-431-55354-0
eBook Packages: MedicineMedicine (R0)