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The Role of Physical Activity in the Prevention of Atherosclerosis: Focus on Oxidative Stress and Oxidised Low-Density Lipoprotein

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Physical Activity, Exercise, Sedentary Behavior and Health

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Abstract

Oxidative stress and inflammatory conditions are associated with an increased risk of atherosclerosis and cardiovascular disease. A large body of evidence supports the notion that higher intensity and/or longer duration exercise training can reduce many cardiovascular disease risk factors including oxidative stress and oxidised low-density lipoprotein. Although physical activity guidelines suggest that adults should engage in at least 150 min of physical activity each week, estimates in many countries suggest that many individuals do not exercise adequately as per guidelines. It is important to determine the minimum level of physical activity required to reduce the risks of cardiovascular disease and atherosclerosis. Thus, the authors conducted a series of investigations to examine the influence of daily physical activity or low-volume exercise training on cardiovascular disease risk factors including oxidative stress markers and oxidised low-density lipoprotein concentration in older adults. We demonstrate that daily physical activity and a low-volume walking program (<150 min/week) improved oxidative stress status in older adults. The implications of the research findings may encourage more people to incorporate a small amount of physical activity into their lives, and translate to prevention of cardiovascular disease and atherosclerosis in the long term.

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Author information

Authors and Affiliations

  1. Department of Health and Sports Sciences, Tokyo Gakugei University, Tokyo, Japan

    Masashi Miyashita

  2. Faculty of Sport Sciences, Waseda University, Saitama, Japan

    Masaki Takahashi

  3. The Dong-A Anti-aging Research Institute, Dong-A University, Busan, South Korea

    Jong-Hwan Park

Authors
  1. Masashi Miyashita
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  2. Masaki Takahashi
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  3. Jong-Hwan Park
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Corresponding author

Correspondence to Masashi Miyashita .

Editor information

Editors and Affiliations

  1. Faculty of Sport Sciences, Waseda University, Saitama, Japan

    Kazuyuki Kanosue

  2. Waseda Institute of Sports Nutrition, Waseda University, Saitama, Japan

    Satomi Oshima

  3. School of Kinesiology, Shanghai University of Sport, Shanghai, China

    Zhen-Bo Cao

  4. Faculty of Sport Sciences, Waseda University, Saitama, Japan

    Koichiro Oka

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© 2015 Springer Japan

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Miyashita, M., Takahashi, M., Park, JH. (2015). The Role of Physical Activity in the Prevention of Atherosclerosis: Focus on Oxidative Stress and Oxidised Low-Density Lipoprotein. In: Kanosue, K., Oshima, S., Cao, ZB., Oka, K. (eds) Physical Activity, Exercise, Sedentary Behavior and Health. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55333-5_21

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  • DOI: https://doi.org/10.1007/978-4-431-55333-5_21

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-55332-8

  • Online ISBN: 978-4-431-55333-5

  • eBook Packages: MedicineMedicine (R0)

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