Abstract
Protein kinase C (PKC) is known to play pivotal roles in the various signal transduction pathways in mammalian cells. Its functions have been extensively explored in mammalian cells, whereas those of the PKC of filamentous fungi remain largely unknown, with the exception that PKC is known to function in the cell wall integrity signaling pathway similar to that in the yeast Saccharomyces cerevisiae. Recent advances in the functional analyses of Aspergillus nidulans PKC suggest that it has functions in germination, hyphal morphogenesis, and spore formation under heat stress. These functions are suppression of apoptosis induction and the establishment of cell polarity during germination, reestablishment of hyphal polarity after depolarization, and repression of conidiation. In this chapter, we present these functions of PKC and describe them in detail.
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Horiuchi, H., Katayama, T. (2015). Protein Kinase C of Filamentous Fungi and Its Roles in the Stresses Affecting Hyphal Morphogenesis and Conidiation. In: Takagi, H., Kitagaki, H. (eds) Stress Biology of Yeasts and Fungi. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55248-2_12
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