Abstract
Intraoperative graft evaluation is important because early graft failure is not rare. Several investigators have reported that graft failure at one year after surgery is approximately 20 % and immediate graft failure occurs in 3.2 % of the grafts (7.6 % of patients) during surgery. These early failures are often associated with technical issues that could be solved promptly if adequately diagnosed intraoperatively. Transit-time flow measurement (TTFM) and intraoperative fluorescence imaging (IFI) are currently most commonly used systems for intraoperative graft assessment. Both systems will reliably detect occluded grafts but cannot consistently detect more minor, nonocclusive abnormalities. The strengths of the IFI system are that it is a safe, simple, and repeatable technique, but its limitations are that it only provides a semiquantitative estimate of graft flow and does not show accurate anastomotic quality. On the other hand, TTFM provides more objective measurements of graft flow but is more likely to both underestimate and overestimate the need for graft revision. High-frequency epicardial ultrasound effectively helps the surgeons to cope with intraoperative challenges: (1) identify the location of target coronary arteries, (2) select the optimal anastomotic sites, and (3) assess the quality of constructed anastomoses.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Poirier NC, Carrier M, Lesperance J et al (1999) Quantitative angiographic assessment of coronary anastomoses performed without cardiopulmonary bypass. J Thorac Cardiovasc Surg 117:292–297
Nathoe HM, van Dijk D, Jansen EW et al (2003) A comparison of on-pump and off-pump coronary bypass surgery in low-risk patients. N Engl J Med 348:394–402
Widimsky P, Straka Z, Stros P et al (2004) One-year coronary bypass graft patency: a randomized comparison between off-pump and on-pump surgery angiographic results of the PRAGUE-4 trial. Circulation 110:3418–3423
Lingaas PS, Hol PK, Lundblad R et al (2004) Clinical and angiographic outcome of coronary surgery with and without cardiopulmonary bypass: a prospective randomized trial. Heart Surg Forum 7:37–41
Khan NE, DeSouza A, Mister R et al (2004) A randomized comparison of off-pump and on-pump multivessel coronary artery bypass surgery. N Engl J Med 350:21–28
Puskas JD, Williams WH, Mahoney EM et al (2004) Off-pump vs conventional coronary artery bypass grafting: early and 1-year graft patency, cost, and quality-of-life outcomes: a randomized trial. JAMA 291:1841–1849
Alexander JH, Hafley G, Harrington RA et al (2005) Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: a randomized controlled trial. JAMA 294:2446–2454
Yusuf S, Zucker D, Peduzzi P et al (1994) Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration. Lancet 344:563–570
D’Ancona G, Karamanoukian HL, Ricci M et al (2000) Graft revision after transit time flow measurement in off-pump coronary artery bypass grafting. Eur J Cardiothorac Surg 17:287–293
Magee MJ, Alexander JH, Hafley G, Ferguson TB Jr, Gibson CM, Harrington RA, Peterson ED, Califf RM, Kouchoukos NT, Herbert MA, Mack MJ, PREVENT IV Investigators (2008) Coronary artery bypass graft failure after on-pump and off-pump coronary artery bypass: findings from PREVENT IV. Ann Thorac Surg 85:494–499
Lytle B, Blackstone E, Loop F et al (1999) Two internal thoracic artery grafts are better than one. J Thorac Cardiovasc Surg 117:855–872
Taggart DP, D’Amico R, Altman DG (2001) Effect of arterial revascularisation on survival: a systematic review of studies comparing bilateral and single internal mammary arteries. Lancet 358:870–875
Abu-Omar Y, Taggart DP (2002) Off-pump coronary artery bypass grafting. Lancet 360:327–330
Parolari A, Alamanni F, Polvani G et al (2005) Meta-analysis of randomized trials comparing off-pump with on-pump coronary artery bypass graft patency. Ann Thorac Surg 80:2121–2125
Shroyer AL, Grover FL, Hattler B, Collins JF, McDonald GO, Kozora E, Lucke JC, Baltz JH, Novitzky D, Veterans Affairs Randomized On/Off Bypass (ROOBY) Study Group (2009) On-pump versus off-pump coronary-artery bypass surgery. N Engl J Med 361:1827–1837
Hol PK, Lingaas PS, Lundblad R et al (2004) Intraoperative angiography leads to graft revision in coronary artery bypass surgery. Ann Thorac Surg 78:502–505
Falk V, Walther T, Philippi A et al (1995) Thermal coronary angiography for intraoperative patency control of arterial and saphenous vein coronary artery bypass grafts: results in 370 patients. J Card Surg 10:147–160
Canver CC, Dame NA (1994) Ultrasonic assessment of internal thoracic artery graft flow in the revascularized heart. Ann Thorac Surg 58:135–138
Taggart DP, Choudhary B, Anastasiadis K et al (2003) Preliminary experience with a novel intraoperative fluorescence imaging technique to evaluate the patency of bypass grafts in total arterial revascularization. Ann Thorac Surg 75:870–873
D’Ancona G, Karamanoukian HL, Ricci M et al (2000) Graft revision after transit time flow measurement in off-pump coronary artery bypass grafting. Eur J Cardiothorac Surg 17:287–293
Kim KB, Kang CH, Lim C (2005) Prediction of graft flow impairment by intraoperative transit time flow measurement in off-pump coronary artery bypass using arterial grafts. Ann Thorac Surg 80:594–598
Balacumaraswami L, Taggart DP (2007) Intraoperative imaging techniques to assess coronary artery bypass graft patency. Ann Thorac Surg 83:2251–2257
Kim KB, Kang CH, Lim C (2005) Prediction of graft flow impairment by intraoperative transit time flow measurement in off-pump coronary artery bypass using arterial grafts. Ann Thorac Surg 80:594–598
Di Giammarco G, Pano M, Cirmeni S et al (2006) Predictive value of intraoperative transit-time flow measurement for short-term graft patency in coronary surgery. J Thorac Cardiovasc Surg 132:468–474
Tokuda Y, Song MH, Ueda Y et al (2007) Predicting early coronary artery bypass graft failure by intraoperative transit time flow measurement. Ann Thorac Surg 84:1928–1933
Hirotani T, Kameda T, Shirota S et al (2001) An evaluation of the intraoperative transit time measurements of coronary bypass flow. Eur J Cardiothorac Surg 19:848–852
Hol PK, Fosse E, Mork BE et al (2001) Graft control by transit time flow measurement and intraoperative angiography in coronary artery bypass surgery. Heart Surg Forum 4:254–257
Speich R, Saesseli B, Hoffmann U et al (1988) Anaphylactoid reaction after indocyanine-green administration. Ann Intern Med 109:345–346
Yasuda T, Watanbe G, Tomita S (2005) Transaortic injection technique in fluorescence imaging: novel intraoperative assessment of anastomosis in off-pump coronary artery bypass grafting. J Thorac Cardiovasc Surg 130:560–561
Rubens FD, Ruel M, Fremes SE (2002) A new and simplified method for coronary and graft imaging during CABG. Heart Surg Forum 5:141–144
Reuthebuch O, Haussler A, Genoni M et al (2004) Novadaq SPY: intraoperative quality assessment in off-pump coronary artery bypass grafting. Chest 125:418–424
Balacumaraswami L, Abu-Omar Y, Anastasiadis K et al (2004) Does off-pump total arterial grafting increase the incidence of intraoperative graft failure? J Thorac Cardiovasc Surg 128:238–244
Takahashi M, Ishikawa T, Higashidani K et al (2004) SPYTM: an innovative intra-operative imaging system to evaluate graft patency during off-pump coronary artery bypass grafting. Interact CardioVasc Thorac Surg 3:479–483
Desai ND, Miwa S, Kodama D et al (2005) Improving the quality of coronary bypass surgery with intraoperative angiography: validation of a new technique. J Am Coll Cardiol 46:1521–1525
Handa T, Katare RG, Nishimori H, Wariishi S, Fukutomi T, Yamamoto M, Sasaguri S, Sato T (2010) New device for intraoperative graft assessment: HyperEye charge-coupled device camera system. Gen Thorac Cardiovasc Surg 58:68–77
Handa T, Katare RG, Sasaguri S, Sato T (2009) Preliminary experience for the evaluation of the intraoperative graft patency with real color charge-coupled device camera system: an advanced device for simultaneous capturing of color and near-infrared images during coronary artery bypass graft. Interact Cardiovasc Thorac Surg 9:150–154
Kuroyanagi S, Asai T, Suzuki T (2012) Intraoperative fluorescence imaging after transit-time flow measurement during coronary artery bypass grafting. Innov (Phila) 7:435–440
Balacumaraswami L, Abu-Omar Y, Choudhary B et al (2005) A comparison of transit-time flowmetry and intraoperative fluorescence imaging for assessing coronary artery bypass graft patency. J Thorac Cardiovasc Surg 130:315–320
Desai ND, Miwa S, Kodama D et al (2006) A randomized comparison of intraoperative indocyanine green angiography and transit-time flow measurement to detect technical errors in coronary bypass grafts. J Thorac Cardiovasc Surg 132:585–594
Isringhaus H (1990) Epicardial coronary artery imaging. Echocardiography 7:253–259
Hayakawa M, Asai T, Kinoshita T, Suzuki T, Shiraishi S (2013) Target vessel detection by epicardial ultrasound in off-pump coronary bypass surgery. Innov (Phila) 8:249–252
Sahn DJ, Barratt-Boyes BG, Graham K, Kerr A, Roche A, Hill D, Brandt PWT, Copeland JG, Mammana R, Temkin LP, Glenn W (1982) Ultrasonic imaging of the coronary arteries in open-chest humans: evaluation of coronary atherosclerotic lesions during cardiac surgery. Circulation 66:1034–1044
Eikelaar JHR, Meijer R, van Boven WJ, Klein P, Gründeman PF, Borst C (2002) Epicardial 10-MHz ultrasound in off-pump coronary bypass surgery: a clinical feasibility study using a minitransducer. J Thorac Cardiovasc Surg 124:785–789
Budde RPJ, Bakker PFA, Meijer R, Borst C, Gründeman PF (2006) Ultrasound mini-transducer with malleable handle for coronary artery surgery. Ann Thorac Surg 81:322–326
Suematsu Y, Takamoto S, Ohtsuka T (2001) Intraoperative echocardiographic imaging of coronary arteries and graft anastomoses during coronary artery bypass grafting without cardiopulmonary bypass. J Thorac Cardiovasc Surg 122:1147–1154
Stein H, Smith JM, Robinson JR, Katz MR (2006) Target vessel detection and coronary anastomosis assessment by intraoperative 12-MHz ultrasound. Ann Thorac Surg 82:1078–1084
Hiratzka LF, McPherson DD, Lamberth WC Jr, Brandt B 3rd, Armstrong ML, Schröder E, Hunt M, Kieso R, Megan MD, Tompkins OK, Marcus ML, Kerber RE (1986) Intraoperative evaluation of coronary artery bypass graft anastomoses with high frequency epicardial echocardiography: experimental validation and initial patient studies. Circulation 73:1199–1205
Hiratzka LF, McPherson DD, Brandt B 3rd, Lamberth WC Jr, Sirna S, Marcus ML, Kerber RE (1987) The role of intraoperative high-frequency epicardial echocardiography during coronary artery revascularization. Circulation 76:V33–V38
Oda K, Hirose K, Nishimori H, Sato K, Yamashiro T, Ogoshi S (1998) Assessment of internal thoracic artery graft with intraoperative color Doppler ultrasonography. Ann Thorac Surg 66:79–81
Ishikura F, Matsuwaka R, Sakakibara T, Sakata Y, Hirayama A, Kodama K (1998) Clinical application of power Doppler imaging to visualize coronary arteries in human beings. J Am Soc Echocardiogr 11:219–227
Arruda AM, Dearani JA, Click RL, Ishikura F, Seward JB (1999) Intraoperative application of power Doppler imaging: visualization of myocardial perfusion after anastomosis of left internal thoracic artery to left anterior descending coronary artery. J Am Soc Echocardiogr 12:650–654
Suematsu Y, Ohtsuka T, Miyairi T, Motomura N, Takamoto S (2002) Ultrasonic evaluation of graft anastomoses during coronary artery bypass grafting without cardiopulmonary bypass. Ann Thorac Surg 74:273–275
Haaverstad R, Vitale N, Williams RI, Fraser AG (2002) Epicardial colour-Doppler scanning of coronary artery stenoses and graft anastomoses. Scand Cardiovasc J 36:95–99
Haaverstad R, Vitale N, Tjomsland O, Tromsdal A, Torp H, Samstad SO (2002) Intraoperative color Doppler ultrasound assessment of LIMA-to-LAD anastomoses in off-pump coronary artery bypass grafting. Ann Thorac Surg 74:S1390–S1394
Miwa S, Nishina T, Ueyama K, Kameyama T, Ikeda T, Nishimura K, Komeda M (2004) Visualization of intramuscular left anterior descending coronary arteries during off-pump bypass surgery. Ann Thorac Surg 77:344–346
Hol PK, Andersen K, Skulstad H, Halvorsen PS, Lingaas PS, Andersen R, Bergsland J, Fosse E (2007) Epicardial ultrasonography: a potential method for intraoperative quality assessment of coronary bypass anastomoses? Ann Thorac Surg 84:801–807
Schiller W, Rudorf H, Tiemann K, Probst C, Mellert F, Welz A (2007) Detection of coronary arteries and evaluation of anastomoses with a commercially available 15-MHz, broadband, linear array transducer. Heart Surg Forum 10:E387–E391
Suematsu Y, Takamoto S, Ohtsuka T, Motomura N, Miyairi T (2002) Power Doppler imaging for detection of harvest injury of internal mammary artery. Asian Cardiovasc Thorac Ann 10:89–91
Budde RPJ, Meijer R, Dessing TC, Borst C, Gründeman PF (2005) Detection of construction errors in ex-vivo coronary artery anastomoses by 13 MHz epicardial ultrasonography. J Thorac Cardiovasc Surg 129:1078–1083
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer Japan
About this chapter
Cite this chapter
Kinoshita, T., Asai, T. (2016). Intraoperative Graft Assessment OPCAB Made in Japan. In: Asai, T., Ochi, M., Yokoyama, H. (eds) Off-Pump Coronary Artery Bypass. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54986-4_18
Download citation
DOI: https://doi.org/10.1007/978-4-431-54986-4_18
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-54985-7
Online ISBN: 978-4-431-54986-4
eBook Packages: MedicineMedicine (R0)