LD for Lung Transplantation

  • Hiroshi Date


Living-donor lobar lung transplantation (LDLLT) has been performed as a lifesaving procedure for critically ill patients who are unlikely to survive the long wait for cadaveric lungs. In this relatively new procedure, the right and left lower lobes from two healthy donors are implanted in the recipient in place of the whole right and left lungs, respectively. Although immediate family members have been the only donors in Japan, non-Japanese institutions have accepted extended family members and unrelated individuals. Potential donors should be competent, willing to donate free of coercion, medically and psychosocially suitable, fully informed of the risks and benefits as a donor, and fully informed of risks, benefits, and alternative treatment available to the recipient. Morbidity rates after donor lobectomy varied from 20 % to 60 % but there has been no reported perioperative mortality of a lung donor. Donor forced vital capacity decreased by 11–16 %, indicating that it was preserved better than expected. The survival of recipients receiving LDLLT was similar or better than cadaveric lung transplantation. On the other hand, long-term outcomes of live donors have not been well documented. More studies will be needed to understand the experience of live lung donors.


Force Vital Capacity Lower Lobe Bronchiolitis Obliterans Extended Family Member Inferior Pulmonary Vein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Japan 2014

Authors and Affiliations

  1. 1.The Department of Thoracic SurgeryKyoto University Graduate School of MedicineKyotoJapan

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