DCD for Pancreas Transplantation

  • Toshinori Ito


Before inclusion of the concept of brain death into law in the mid- to late 1970s, all organ transplantations came from cadaveric donors after cardiac death (DCD), i.e., non-heart-beating donors (NHBDs). However, the introduction of brain-dead donors (BDD, heart-beating donors) led to better outcomes, as transplant organs were perfused with oxygenated blood right until the time for perfusion and cooling with preservation solution at organ procurement. Thus, DCDs were generally no longer utilized, except in Japan.

However, a growing discrepancy between demand for organs and their availability from BDDs led to a reevaluation of the use of DCD, and some transplant centers are now trying to use such donors to expand their potential pool of organs.


Brain Death Plasma Glucose Level Warm Ischemia Organ Procurement Ischemia Group 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Kootsra G et al. Categories of non-heart beating donors. Transplant Proc. 1995;27:2893–4.Google Scholar
  2. 2.
    Izukura M. An experimental study on the segmental pancreatic transplantation: the influence of warm ischemia on the pancreatic endocrine functions in dogs. Med J Osaka Univ. 1988;40(3):39–57.Google Scholar
  3. 3.
    Tojimbara S, Teraoka S, Babazono T, et al. Long-term outcome after combined pancreas and kidney transplantation from non-heart cadaver donors. Transplant Proc. 1998;30:3793–4.PubMedCrossRefGoogle Scholar
  4. 4.
    Salvalaggio PR, Davies DB, Fernandez LA, et al. Outcomes of pancreas transplantation in the United States using cardiac death donors. Am J Transplant. 2006;65(Pt 1):1059–65.CrossRefGoogle Scholar
  5. 5.
    Muthusamy ASR, Mumford L, Hudosn A, et al. Pancreas transplantation from donors after circulatory death from the United Kingdom. Am J Transplant. 2012;12:2150–6.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Japan 2014

Authors and Affiliations

  1. 1.Departments of Complementary and Alternative Medicine and Gastroenterological Surgery, Graduate School of MedicineOsaka UniversitySuitaJapan

Personalised recommendations