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ECD for Kidney Transplantation

  • Naoto Matsuno
Chapter

Abstract

Because of the shortage of organs for kidney transplantation, there has been greater interest in recent years in the use of expanded criteria donors (ECDs), defined as brain-dead donors aged ³60 years or donors aged ³50 years with a history of hypertension plus terminal donor serum creatinine £1.5mg/dL, or death resulting from a cerebrovascular accident. Although long-term outcomes of ECD kidneys has been worse than that of standard-criteria donor kidneys, mortality is decreased with ECD kidney transplant compared with remaining on dialysis therapy. This review focuses on the use of ECDs to define donor and recipient selection criteria, including the usefulness of donor kidney biopsies as a pretransplant test for dual kidney transplantation. In addition, short- and long-term survival for younger and older patients who received ECD kidney transplantation compared with remaining on dialysis therapy is reviewed.

Keywords

Human Leukocyte Antigen Graft Survival Graft Loss Donor Kidney Delay Graft Function 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Japan 2014

Authors and Affiliations

  1. 1.Division for Innovative Surgery and TransplantationNational Center for Child Health and DevelopmentTokyoJapan

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