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LD for Liver Transplantation

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Abstract

First of all, donation should be based on voluntary will and the donor should be healthy. A donor candidate should be fully informed about benefits and adverse effects to the donor and recipient after transplantation and the expected prognosis of the recipient. Japanese transplant law requires confirmation of voluntary will, fully consented form, and full understanding of the risks and benefits to the donor, and a psychologist should confirm it. A donor is chosen from relatives including spouses. Emotional relatives should be strictly assessed by ethical committees to avoid organ trade.

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References

  1. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412–9.

    Article  CAS  PubMed  Google Scholar 

  2. Kiuchi T, Harada H, Matsukawa H, Kasahara M, Inomata Y, Uemoto S, Asonuma K, Egawa H, Maruya E, Saji H, Tanaka K. One-way donor-recipient HLA-matching as a risk factor for graft-versus-host disease in living-related liver transplantation. Transpl Int. 1998;11 Suppl 1:S383–4.

    Article  PubMed  Google Scholar 

  3. Miyagawa-Hayashino A, Yoshizawa A, Uchida Y, Egawa H, Yurugi K, Masuda S, Minamiguchi S, Maekawa T, Uemoto S, Haga H. Progressive graft fibrosis and donor-specific HLA antibodies in pediatric late liver allografts. Liver Transpl. 2012;18(11):1333–42.

    Google Scholar 

  4. Egawa H. Minimizing the risks for living donors of right lobe liver grafts. Nat Rev Gastroenterol Hepatol. 2011;8(5):251–2.

    PubMed  Google Scholar 

  5. Kiuchi T, Kasahara M, Uryuhara K, Inomata Y, Uemoto S, Asonuma K, Egawa H, Fujita S, Hayashi M, Tanaka K. Impact of graft size mismatching on graft prognosis in liver transplantation from living donors. Transplantation. 1999;67(2):321–7.

    Article  CAS  PubMed  Google Scholar 

  6. Kawasaki S, Makuuchi M, Ishizone S, Matsunami H, Terada M, Kawarazaki H. Liver regeneration in recipients and donors after transplantation. Lancet. 1992;339(8793):580–1.

    Article  CAS  PubMed  Google Scholar 

  7. Kasahara M, Fukuda A, Yokoyama S, Sato S, Tanaka H, Kuroda T, et al. Living donor liver transplantation with hyperreduced left lateral segments. J Pediatr Surg. 2008;43:1575–8.

    Article  PubMed  Google Scholar 

  8. Mizuta K, Yasuda Y, Egami S, Sanada Y, Wakiya T, Urahashi T, et al. Living donor liver transplantation for neonates using segment 2 monosegment graft. Am J Transplant. 2010;10:2547–52.

    Article  CAS  PubMed  Google Scholar 

  9. Iwasaki M, Takada Y, Hayashi M, Minamiguchi S, Haga H, Maetani Y, Fujii K, Kiuchi T, Tanaka K. Noninvasive evaluation of graft steatosis in living donor liver transplantation. Transplantation. 2004;78(10):1501–5.

    Article  PubMed  Google Scholar 

  10. Egawa H, Teramukai S, Haga H, Tanabe M, Fukushima M, Shimazu M. Present status of ABO-incompatible living donor liver transplantation in Japan. Hepatology. 2008;47(1):143–52.

    Article  PubMed  Google Scholar 

  11. Egawa H, Ohmori K, Haga H, Tsuji H, Yurugi K, Miyagawa-Hayashino A, et al. B-cell surface marker analysis for improvement of rituximab prophylaxis in ABO-incompatible adult living donor liver transplantation. Liver Transplant. 2007;13(4):579–88.

    Article  Google Scholar 

  12. Ikegami T, Taketomi A, Yoshizumi H, Harada N, Iguchi T, Hashimoto N, et al. Rituximab, IVIG, and plasma exchange without graft local infusion treatment; a new protocol in ABO incompatible living donor liver transplantation. Transplantation. 2009;88:303–7.

    Article  CAS  PubMed  Google Scholar 

  13. Takayama T, Makuuchi M, Kubota K, Sano K, Harihara Y, Kawarasaki H. Living-related transplantation of left liver plus caudate lobe. J Am Coll Surg. 2000;190(5):635–8.

    Article  CAS  PubMed  Google Scholar 

  14. Sugawara Y, Makuuchi M, Imamura H, Kaneko J, Kokudo N. Outflow reconstruction in extended right liver grafts from living donors. Liver Transplant. 2003;9(3):306–9.

    Article  Google Scholar 

  15. Ito T, Kiuchi T, Yamamoto H, Oike F, Ogura Y, Fujimoto Y, et al. Changes in portal venous pressure in the early phase after living donor liver transplantation: pathogenesis and clinical implications. Transplantation. 2003;75(8):1313–7.

    Article  PubMed  Google Scholar 

  16. Ogura Y, Hori T, El Moghazy WM, Yoshizawa A, Oike F, Mori A, et al. Portal pressure <15 mm Hg is a key for successful adult living donor liver transplantation utilizing smaller grafts than before. Liver Transplant. 2010;16(6):718–28.

    Google Scholar 

  17. Uemoto S, Sugiyama K, Marusawa H, Inomata Y, Asonuma K, Egawa H, Kiuchi T, Miyake Y, Tanaka K, Chiba T. Transmission of hepatitis B virus from hepatitis B core antibody-positive donors in living related liver transplants. Transplantation. 1998;65(4):494–9.

    Article  CAS  PubMed  Google Scholar 

  18. Asonuma K, Ohya Y, Isono K, Takeichi T, Yamamoto H, Lee KJ, Okumura K, Ando Y, Inomata Y. Current state of domino transplantation in Japan in terms of surgical procedures and de novo amyloid neuropathy. Amyloid. 2012;19 Suppl 1:75–7.

    Article  PubMed  Google Scholar 

  19. Tincani G, Hoti E, Andreani P, Ricca L, Pittau G, Vitale V, Blandin F, Adam R, Castaing D, Azoulay D. Operative risks of domino liver transplantation for the familial amyloid polyneuropathy liver donor and recipient: a double analysis. Am J Transplant. 2011;11(4):759–66.

    Article  CAS  PubMed  Google Scholar 

  20. The Japanese Liver Transplantation Society. Liver transplantation in Japan: registry by the japanese liver transplantation society. Ishoku. 2010;46:624–36.

    Google Scholar 

  21. Hashikura Y, Ichida T, Umeshita K, Kawasaki S, Mizokami M, Mochida S, Yanaga K, Monden M, Kiyosawa K, Japanese Liver Transplantation Society. Donor complications associated with living donor liver transplantation in Japan. Transplantation. 2009;88:110–4.

    Article  PubMed  Google Scholar 

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Correspondence to Hiroto Egawa .

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© 2014 Springer Japan

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Egawa, H. (2014). LD for Liver Transplantation. In: Asano, T., Fukushima, N., Kenmochi, T., Matsuno, N. (eds) Marginal Donors. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54484-5_12

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  • DOI: https://doi.org/10.1007/978-4-431-54484-5_12

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  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-54483-8

  • Online ISBN: 978-4-431-54484-5

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