• Takayuki Kinoshita


In the surgical treatment of breast cancer, conservative treatment and sentinel lymph node biopsy have already become the standard of care. In addition to being less invasive, treatments are expected to have good aesthetic outcomes. In Japan, the incidence of breast cancer (Fig. 1.1) and the detection rate for early-stage disease have increased due to widespread use of mammography and advances in diagnostic imaging, as is the case in other developed countries. Given this historical background, nonsurgical ablative therapies, noninvasive surgical therapies, have started to attract attention due to patient demand. The nonsurgical ablative therapies used in clinical practice for breast cancer are cryoablation, high-intensity focused ultrasound (HIFU), and radiofrequency ablation (RFA). In Japan, RFA became widespread quickly because of the prevalence and convenience of the device. In this book, an outline of the research on RFA funded by the Japan Agency for Medical Research and Development (AMED), prospects for RFA, and the current status of cryoablation and HIFU are discussed.


Breast Cancer Sentinel Lymph Node Biopsy Breast Conservation Surgery Japanese Breast Cancer Society Multicentre Clinical Study 
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Copyright information

© Springer Japan 2016

Authors and Affiliations

  1. 1.Division of Breast SurgeryNational Cancer Center HospitalTokyoJapan

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