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Analysis of Pancreatic Tissue Injury Caused by Ultrasonically Activated Devices

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The Malaysia-Japan Model on Technology Partnership

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Abstract

Pancreatic fistula has been reported to occur more frequently in laparoscopic surgery than conventional open surgery. An ultrasonically activated device (USAD) has been raised as one of the cause of that, because of its frequent usage in laparoscopic surgeries and allegedly harmful side effect such as cavitation and/or lateral thermal effect. This research has been conducted to determine whether USAD could be the direct cause of pancreatic fistula using an animal model. The pancreas of a 3-month-old domestic pig weighing 30 kg was exposed under general anesthesia. USADs were activated in contact with the pancreas with various activation times and locations of the blades, and histopathological analyses of the specimens were performed. As a result, coagulation necrosis was observed at activation sites in all specimens. However, much less protein clotting covering the damaged sites was observed with USADs compared with electric scalpels. These data suggest that USADs are more likely to cause pancreatic tissue damage which leads to pancreatic fistula compared with conventional electric scalpels.

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Author information

Authors and Affiliations

  1. Graduate school of Engineering, Chiba University, Chiba, 2630022, Japan

    Bik Ee Lau

  2. Graduate School of Medicine, Chiba University, Chiba, Japan

    Tao Gao

  3. Research Center for Frontier Medical Engineering, Chiba University, Chiba, Japan

    Hideki Hayashi

Authors
  1. Bik Ee Lau
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  2. Tao Gao
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  3. Hideki Hayashi
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Corresponding author

Correspondence to Bik Ee Lau .

Editor information

Editors and Affiliations

  1. Universiti Malaysia Sarawak, Sawawak, Malaysia

    Khairuddin Ab. Hamid

  2. Meiji University, Tokyo, Japan

    Osamu Ono

  3. Sony Corporation, Tokyo, Japan

    Anas Muhamad Bostamam

  4. The University of Tokyo, Tokyo, Japan

    Amy Poh Ai Ling

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© 2015 Springer Japan

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Lau, B.E., Gao, T., Hayashi, H. (2015). Analysis of Pancreatic Tissue Injury Caused by Ultrasonically Activated Devices. In: Ab. Hamid, K., Ono, O., Bostamam, A., Poh Ai Ling, A. (eds) The Malaysia-Japan Model on Technology Partnership. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54439-5_19

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  • DOI: https://doi.org/10.1007/978-4-431-54439-5_19

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  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-54438-8

  • Online ISBN: 978-4-431-54439-5

  • eBook Packages: EngineeringEngineering (R0)

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