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Inflammation and Cytokines in Endometriosis

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Endometriosis

Abstract

Endometriosis, a common disease among women of reproductive age, is characterized by the presence and growth of endometrial tissue (glands and stroma) outside the uterus. Dysmenorrhea and infertility common in endometriosis compromise the quality of life of reproductive age women. Despite a long history of clinical experience and experimental research, endometriosis remains an enigma, and its pathogenesis is still controversial. The peritoneal fluid (PF) of women with endometriosis contains an increased number of activated macrophages that secrete a variety of local products, such as growth factors and cytokines. In this chapter, we review the current understanding of the role of cytokines in the pathogenesis of endometriosis.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Faculty of Medicine, Sanin Rosai Hospital, Yonago, Japan

    Tomio Iwabe

  2. Department of Obstetrics and Gynecology, Faculty of Medicine, Tottori University, Yonago, Japan

    Tasuku Harada

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  1. Tomio Iwabe
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  2. Tasuku Harada
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Correspondence to Tomio Iwabe .

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Editors and Affiliations

  1. Department of Obstetrics and Gynecology, Tottori University Faculty of Medicine, Yonago, Tottori, Japan

    Tasuku Harada

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Iwabe, T., Harada, T. (2014). Inflammation and Cytokines in Endometriosis. In: Harada, T. (eds) Endometriosis. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54421-0_7

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  • DOI: https://doi.org/10.1007/978-4-431-54421-0_7

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