Plasma Exchange

  • Daisuke Katagiri
  • Hideo Kurosawa


  • Plasma exchange (PE) involves the withdrawal of blood from the circulation, centrifugal separation of the blood into plasma and cells, and return of the cellular components suspended in an inert medium.

  • Fresh frozen plasma (FFP) is used for replacement of proteins (with the exception of albumin), such as clotting factors.

  • The combination of PE and hemodialysis (HD) may be used to avoid development of hypocalcemia or hyponatremia caused by FFP.


Plasma Exchange Fresh Freeze Plasma Blood Flow Rate Replacement Solution Calcium Gluconate 
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Copyright information

© Springer Japan 2014

Authors and Affiliations

  1. 1.Department of Nephrology & EndocrinologyUniversity Hospital, The University of TokyoTokyoJapan
  2. 2.Department of Hemodialysis & ApheresisUniversity Hospital, The University of TokyoTokyoJapan

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