Apheresis in Children



  1. 1.

    It has become possible to perform apheresis in small children owing to the development and clinical application of specialized blood purification devices and equipment, such as vascular catheters for small children and small-volume extracorporeal circuits and modules.

  2. 2.

    Technical considerations include ensuring vascular access, reducing extracorporeal volume, preventing hypothermia, and providing proper anti-coagulant treatment.



Kawasaki Disease Plasma Exchange Continuous Renal Replacement Therapy Hemolytic Uremic Syndrome Fresh Freeze Plasma 
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  1. 1.
    Wong ECC, Balogun RA (2012) Therapeutic apheresis in ­pediatrics: technique adjustments, indications and nonindications, a plasma exchange focus. J Clin Apheresis 27:132–137PubMedCrossRefGoogle Scholar
  2. 2.
    Waters AM, Licht C (2011) A HUS caused by complement deregulation: new therapies on the horizon. Pediatr Nephrol 26:41–54PubMedCrossRefGoogle Scholar
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    Soma I, Hattori M (2011) Vascular access for pediatric patients. Rinsho-Touseki 27:839–848 (in Japanese)Google Scholar
  4. 4.
    Soma I, Hattori M (2010) Blood purification in children. In: Apheresis manual revised 3 version. Japanese Society for Apheresis, Syujunsya, pp 184–191 (in Japanese)Google Scholar
  5. 5.
    Goldstein SL (2012) Therapeutic apheresis in children: special considerations. Semin Dial 25:165–170PubMedCrossRefGoogle Scholar

Copyright information

© Springer Japan 2014

Authors and Affiliations

  1. 1.Department of Pediatric NephrologyTokyo Women’s Medical University, School of MedicineTokyoJapan

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