Abstract
CD34 positive hematopoietic stem cells are mobilized from bone marrow to peripheral blood by G-CSF administration, and collected using a blood cell separator that uses a centrifuge to separate mononuclear cells.
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References
Guideline for peripheral blood stem cell mobilization and collection from healthy donors for allogeneic peripheral blood stem cell transplantation. The Japan Society for hematopoietic cell transplantation. The Japan Society of transfusion medicine and cell therapy (a revised edition version 3), 21 April 2003
Lee V, Li CK, Shing MM et al (2000) Single vs twice daily G-CSF dose for peripheral blood stem cells harvest in normal donors and children with non-malignant diseases. Bone Marrow Transplant 25:931–935
Kröger N, Renges H, Krüger W et al (2000) A randomized comparison of once versus twice daily recombinant human granulocyte colony-stimulating factor (filgrastim) for stem cell mobilization in healthy donors for allogeneic transplantation. Br J Haematol 111:761–765
Stroncek DF, Clay ME, Petzoldt ML et al (1996) Treatment of normal individuals with granulocyte-colony-stimulating factor: donor experiences and the effects on peripheral blood CD34+ cell counts and on the collection of peripheral blood stem cells. Transfusion 36:601–610
Watts MJ, Addison I, Ings SJ et al (1998) Optimal timing for collection of PBPC after glycosylated G-CSF administration. Bone Marrow Transplant 21:365–368
Basquiera AL, Abichain P, Damonte JC et al (2006) The number of CD34(+) cells in peripheral blood as a predictor of the CD34(+) yield in patients going to autologous stem cell transplantation. J Clin Apher 21:92–5
Kawakami K, Abe Y, Imataki O et al (2006) Determining the time of harvesting peripheral blood stem cells using the HPC, for monitoring hematopoietic progenitor cells, of the automated hematology analyzer XE-2100. Sysmex J 29:39–45
Sutherland DR, Anderson L, Keeney M, Nayar R, Chin-Yee I (1996) The ISHAGE guidelines for CD34+ cell determination by flow cytometry. International Society of Hematotherapy and Graft Engineering. J Hematother 5:213–26
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© 2014 Springer Japan
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Watanabe-Okochi, N. (2014). Peripheral Blood Stem Cell Transplantation. In: Noiri, E., Hanafusa, N. (eds) The Concise Manual of Apheresis Therapy. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54412-8_38
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DOI: https://doi.org/10.1007/978-4-431-54412-8_38
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