Skip to main content

Peripheral Blood Stem Cell Transplantation

  • Chapter
  • First Online:
Book cover The Concise Manual of Apheresis Therapy
  • 1229 Accesses

Abstract

CD34 positive hematopoietic stem cells are mobilized from bone marrow to peripheral blood by G-CSF administration, and collected using a blood cell separator that uses a centrifuge to separate mononuclear cells.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Guideline for peripheral blood stem cell mobilization and ­collection from healthy donors for allogeneic peripheral blood stem cell transplantation. The Japan Society for hematopoietic cell transplantation. The Japan Society of transfusion medicine and cell therapy (a revised edition version 3), 21 April 2003

    Google Scholar 

  2. Lee V, Li CK, Shing MM et al (2000) Single vs twice daily G-CSF dose for peripheral blood stem cells harvest in normal donors and children with non-malignant diseases. Bone Marrow Transplant 25:931–935

    Article  PubMed  CAS  Google Scholar 

  3. Kröger N, Renges H, Krüger W et al (2000) A randomized comparison of once versus twice daily recombinant human granulocyte colony-stimulating factor (filgrastim) for stem cell mobilization in healthy donors for allogeneic transplantation. Br J Haematol 111:761–765

    PubMed  Google Scholar 

  4. Stroncek DF, Clay ME, Petzoldt ML et al (1996) Treatment of normal individuals with granulocyte-colony-stimulating factor: donor experiences and the effects on peripheral blood CD34+ cell counts and on the collection of peripheral blood stem cells. Transfusion 36:601–610

    Article  PubMed  CAS  Google Scholar 

  5. Watts MJ, Addison I, Ings SJ et al (1998) Optimal timing for ­collection of PBPC after glycosylated G-CSF administration. Bone Marrow Transplant 21:365–368

    Article  PubMed  CAS  Google Scholar 

  6. Basquiera AL, Abichain P, Damonte JC et al (2006) The number of CD34(+) cells in peripheral blood as a predictor of the CD34(+) yield in patients going to autologous stem cell transplantation. J Clin Apher 21:92–5

    Article  PubMed  CAS  Google Scholar 

  7. Kawakami K, Abe Y, Imataki O et al (2006) Determining the time of harvesting peripheral blood stem cells using the HPC, for monitoring hematopoietic progenitor cells, of the automated hematology analyzer XE-2100. Sysmex J 29:39–45

    Google Scholar 

  8. Sutherland DR, Anderson L, Keeney M, Nayar R, Chin-Yee I (1996) The ISHAGE guidelines for CD34+ cell determination by flow cytometry. International Society of Hematotherapy and Graft Engineering. J Hematother 5:213–26

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Naoko Watanabe-Okochi .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer Japan

About this chapter

Cite this chapter

Watanabe-Okochi, N. (2014). Peripheral Blood Stem Cell Transplantation. In: Noiri, E., Hanafusa, N. (eds) The Concise Manual of Apheresis Therapy. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54412-8_38

Download citation

  • DOI: https://doi.org/10.1007/978-4-431-54412-8_38

  • Published:

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-54411-1

  • Online ISBN: 978-4-431-54412-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics