Apheresis is one of the possible therapeutic strategies for acute liver failure, such as that caused by fulminant hepatitis and post-surgery liver failure.
Plasma exchange (PE) plays an important role as an artificial liver support (ALS) until progressive hepatocyte necrosis ends and sufficient hepatic regeneration occurs.
Liver transplantation has recently improved the prognosis of fulminant hepatitis. Preoperative conditions, especially hepatic coma, are known to have a great impact on the survival rates associated with liver transplantation. Therefore, apheresis in liver failure is necessary as a bridge therapy to transplantation.
KeywordsLiver Failure Plasma Exchange Acute Liver Failure Fulminant Hepatitis Total Bilirubin Level