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Bleeding Complications and Reduction of Coagulation Factors

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Abstract

  • Bleeding diathesis during apheresis can be caused by anticoagulant drugs, removal of endogenous coagulating factors, or primary diseases.

  • Monitoring is necessary; activated coagulation time as well as direct measurement of fibrinogen and factor XIII levels is indispensable during plasmapheresis with albumin supplementation including double filtration plasmapheresis.

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References

  1. Mokrzycki MH et al (1994) Therapeutic plasma exchange: ­complications and management. Am J Kidney Dis 23(6):817–827

    PubMed  CAS  Google Scholar 

  2. Kaplan AA (2008) Therapeutic plasma exchange: core curriculum 2008. Am J Kidney Dis 52(6):1180–1196

    Article  PubMed  Google Scholar 

  3. Hanafusa N (2011) Theoretical basis of pathogenic substance removal during plasmapheresis. Ther Apher Dial 15(5):421–430

    Article  PubMed  CAS  Google Scholar 

  4. Hanafusa N et al (2007) Double filtration plasmapheresis can decrease factor XIII activity. Ther Apher Dial 11(3):165–170

    Article  PubMed  CAS  Google Scholar 

  5. Hanafusa N et al (2010) Virus removal and eradication by modified double filtration plasmapheresis decreases factor XIII levels. Ther Apher Dial 14(3):287–291

    Article  PubMed  Google Scholar 

  6. Gerlach R et al (2000) Factor XIII deficiency and postoperative hemorrhage after neurosurgical procedures. Surg Neurol 54(3):260–264 (discussion 264–265)

    Article  PubMed  CAS  Google Scholar 

  7. Hanafusa N et al (2013) The effect of different apheresis modalities on coagulation factor XIII level during antibody removal in ABO-blood type incompatible living related renal transplantation. Transfus Apher Sci (in press)

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  8. Hanafusa N et al (2010) A patient whose factor XIII level was decreased by double filtrate plasmapheresis and successfully recovered by infusion of factor XIII concentrate. Ther Apher Dial 14(4):432–433

    Article  PubMed  Google Scholar 

  9. Seishima M et al (2009) Decreased factor XIII activity in a patient with subcutaneous bleeding after double filtration plasmapheresis. Ther Apher Dial 13(3):229–231

    Article  PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Hemodialysis & Apheresis, University Hospital, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan

    Norio Hanafusa

Authors
  1. Norio Hanafusa
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Correspondence to Norio Hanafusa .

Editor information

Editors and Affiliations

  1. Department of Hemodialysis & Apheresis, University Hospital The University of Tokyo, Bunkyo-ku, Tokyo, Japan

    Eisei Noiri

  2. Department of Hemodialysis & Apheresis, University Hospital The University of Tokyo, Bunkyo-ku,, Tokyo, Japan

    Norio Hanafusa

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Hanafusa, N. (2014). Bleeding Complications and Reduction of Coagulation Factors. In: Noiri, E., Hanafusa, N. (eds) The Concise Manual of Apheresis Therapy. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54412-8_18

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  • DOI: https://doi.org/10.1007/978-4-431-54412-8_18

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  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-54411-1

  • Online ISBN: 978-4-431-54412-8

  • eBook Packages: MedicineMedicine (R0)

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