Abstract
Over the past few years, increased attention has been given to stimulus-responsive and/or smart polymeric nanofibers owing to their ability to act as an ‘on–off’ reversible switch. Their structures are uniquely advantageous because their nanoscale features provide an extremely large surface area and high porosity, which increase the sensitivity to external stimuli, whereas their macroscopic features enable facile manipulation as a bulk matter. In addition, polymeric nanofibers can be manufactured at a low cost in large quantities. Indeed, polymeric nanofibers have already been utilized in the clinical field as wound dressings and antiadhesive membranes. Taken together, these advantages on both the nano- and macroscopic scales demonstrate that dynamically and reversibly tunable structures of smart nanofibers have the potential to be utilized for ‘on–off’ delivery of drugs or cells.
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Ebara, M. et al. (2014). Smart Nanofibers. In: Smart Biomaterials. NIMS Monographs. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54400-5_5
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