History: Pancreas

  • Shigeyuki Kawa
  • Takayuki Watanabe
  • Masahiro Maruyama
  • Tetsuya Ito
  • Masafumi Maruyama
  • Yayoi Ozaki
  • Takashi Muraki
  • Hideaki Hamano
  • Norikazu Arakura


IgG4-related disease (IgG4-RD) has come to be recognized as a systemic disorder characterized by high serum IgG4 concentrations and abundant IgG4-positive plasma cell infiltration in affected organs. Autoimmune pancreatitis (AIP) is a major manifestation of this condition, whose close association with IgG4 has been intensively investigated. In this chapter, we focused on the history of the association between AIP and IgG4, which led to the proposal of the new disease concept of IgG4-RD.


Main Pancreatic Duct Autoimmune Pancreatitis Serum IgG4 Concentration Japan Pancreas Society Obliterative Phlebitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Japan 2014

Authors and Affiliations

  • Shigeyuki Kawa
    • 1
  • Takayuki Watanabe
    • 2
  • Masahiro Maruyama
    • 2
  • Tetsuya Ito
    • 2
  • Masafumi Maruyama
    • 2
  • Yayoi Ozaki
    • 2
  • Takashi Muraki
    • 2
  • Hideaki Hamano
    • 3
  • Norikazu Arakura
    • 4
  1. 1.Center for Health, Safety, and Environmental ManagementShinshu UniversityMatsumoto CityJapan
  2. 2.Department of GastroenterologyShinshu University School of MedicineMatsumoto CityJapan
  3. 3.Department of Medical InformationShinshu University School of MedicineMatsumoto CityJapan
  4. 4.Department of Endoscopic Examination CenterShinshu University School of MedicineMatsumoto CityJapan

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