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Evolution in the Dark pp 29–55Cite as

Genome Features of Dark-fly

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Abstract

Recent progress in genome science enables us to determine the whole genome sequences of laboratory-evolved organisms and to address the molecular mechanisms underlying environmental adaptation. We determined the whole genome sequence of Dark-fly and identified many genomic alterations in its genome. Analysis of the population genome structure revealed that about 5 % of genome regions were possibly selected during the Dark-fly history, and that 241 genes in those regions carry mutations. In addition, we identified 28 nonsense mutations in the Dark-fly genome, which probably disrupt or severely affect the function of the gene product. These results revealed unique features of the Dark-fly genome and provided a list of potential candidate genes involved in environmental adaptation. These candidate genes include a light receptor, olfactory receptors, and enzymes related to detoxification and neural development.

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Authors and Affiliations

  1. Global COE Program Graduate School of Science, Kyoto University, Kitashirakawa-Oiwake, Sakyo-ku, Kyoto, 606-8502, Japan

    Naoyuki Fuse

  2. Department of Zoology Graduate School of Science, Kyoto University, Kitashirakawa-Oiwake, Sakyo-ku, Kyoto, 606-8502, Japan

    Tasuku Kitamura, Takashi Haramura & Michio Imafuku

  3. Laboratory of Neuroethology, The Graduate University for Advanced Studies, Shonan Village, Hayama, Kanagawa, 240-0193, Japan

    Kentaro Arikawa

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  1. Naoyuki Fuse
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  2. Tasuku Kitamura
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  3. Takashi Haramura
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  4. Kentaro Arikawa
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  5. Michio Imafuku
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Fuse, N., Kitamura, T., Haramura, T., Arikawa, K., Imafuku, M. (2014). Genome Features of Dark-fly. In: Evolution in the Dark. SpringerBriefs in Biology. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54147-9_4

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