CQ49. Does TSH Suppression Therapy After Surgery for Differentiated Thyroid Carcinoma Improve Survival?

  • Minoru Fujimori
  • Hisato Hara
  • Hidemitsu Tsutsui


Differentiated thyroid carcinoma is thought to be a TSH-dependent tumor. TSH suppression therapy is to avoid recurrence of a differentiated carcinoma by administering an adequate dose of thyroid hormone as postoperative endocrine therapy and suppressing the secretion of TSH from the pituitary gland through its negative feedback. This CQ assessed whether this improves the prognosis.


Thyroid Hormone Thyroid Carcinoma Pituitary Gland Total Thyroidectomy Differentiate Thyroid Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Miyakawa M (2007) (Text in Japanese) Nihon Rinsho 65:2073–2077 (NR)Google Scholar
  2. 2.
    McGriff NJ, Csako G, Gourgiotis L et al (2002) Effects of thyroid hormone suppression therapy on adverse clinical outcomes in thyroid cancer. Ann Med 34:554–564 (SR<RCT>)PubMedCrossRefGoogle Scholar
  3. 3.
    Hovens GC, Stokkel MP, Kievit J (2007) Associations of serum thyrotropin concentrations with recurrence and death in differentiated thyroid cancer. J Clin Endocrinol Metab 92:2610–2615 (RS)PubMedCrossRefGoogle Scholar
  4. 4.
    Cooper DS, Bonny S, Ho M et al (1998) Thyrotropin suppression and disease progression patients with differentiated thyroid cancer: results from the national thyroid cancer treatment cooperative registry. Thyroid 8:737–744 (PS)PubMedCrossRefGoogle Scholar
  5. 5.
    Biondi B, Filwtti S, Schlumgerger M (2005) Thyroid─hormone therapy and thyroid cancer: a reassessment. Nat Clin Pract 1:32–40 (NR)CrossRefGoogle Scholar
  6. 6.
    Cooper DS, Doherty GM, Haugen BR et al (2006) Management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 16:109–142 (Others)PubMedCrossRefGoogle Scholar

Copyright information

© Springer Japan 2013

Authors and Affiliations

  • Minoru Fujimori
    • 1
  • Hisato Hara
    • 2
  • Hidemitsu Tsutsui
    • 3
  1. 1.Department of Breast SurgeryTokyo Medical University, Ibaraki Medical CenterAmimachi, InashikigunJapan
  2. 2.Department of Breast and Endocrine Surgery, Clinical Science, Graduate School of Comprehensive Human SciencesUniversity of TsukubaTsukubaJapan
  3. 3.Department of Thoracic and Thyroid SurgeryTokyo Medical UniversityTokyoJapan

Personalised recommendations