Skip to main content
SpringerLink
Log in

Column 3. Anaplastic Transformation of Differentiated Carcinoma

  • Chapter
  • First Online:
Treatment of Thyroid Tumor

  • 1332 Accesses

Abstract

Rapidly enlarging, hard, immobile tumor, prominent dyspnea, and difficulty swallowing are indicative of anaplastic transformation of differentiated carcinoma. Anaplastic transformation can occur in metastatic lymph nodes and metastatic target organs.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Naito S, Matsui K, Otani N et al (2002) (Text in Japanese) Jibiinkouka Rinsho supplement 109:148–152 (CaseR)

    Google Scholar 

  2. Sakai A, Sugitani I, Kawabata K et al (2007) (Text in Japanese) Naibunpitu Geka 24:151–155 (CaseR)

    Google Scholar 

  3. Ito Y, Higashiyama T, Hirokawa M et al (2008) Prognosis of patients with papillary carcinoma showing anaplastic transformation in regional lymph nodes that were curatively resected. Endocr J 55:985–989 (RS)

    Article  PubMed  Google Scholar 

  4. Inuzuka K, Fujisaki M, Tokura H et al (2004) (Text in Japanese) Rinsho Geka 59:767–771 (CaseR)

    Google Scholar 

  5. Aono H, Muto M, Park T et al (2002) (Text in Japanese) Kyotoshi Byouin 22:53–57 (CaseR)

    Google Scholar 

  6. Quiros RM, Ding HG, Gattuso P et al (2005) Evidence that one subset of anaplastic thyroid carcinomas are derived from papillary carcinomas due to BRAF and p53 mutations. Cancer 103:2261–2268 (RS)

    Article  PubMed  CAS  Google Scholar 

  7. Wang HM, Huang YW, Huang JS et al (2007) Anaplastic carcinoma of the thyroid arising more often from follicular carcinoma than papillary carcinoma. Ann Surg Oncol 14:3011–3018 (RS)

    Article  PubMed  Google Scholar 

  8. Elliott DD, Sherman SI, Busaidy NL et al (2008) Growth factor receptors expression in anaplastic thyroid carcinoma: potential markers for therapeutic stratification. Hum Pathol 39:15–20 (PS)

    Article  PubMed  CAS  Google Scholar 

  9. Wiseman SM, Griffith OL, Deen S et al (2007) Identification of molecular markers altered during transformation of differentiated into anaplastic thyroid carcinoma. Arch Surg 142:717–729 (PS)

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Head and Neck Surgery, National Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Japan

    Masahisa Saikawa

  2. Department of Surgery, Division of Endocrine Surgery, Nippon Medical School, Tokyo, Japan

    Haruki Akasu

Authors
  1. Masahisa Saikawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Haruki Akasu
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Masahisa Saikawa .

Editor information

Editors and Affiliations

  1. Ito Hospital, 4-3-6 Jinguumae, Shibuya-ku, Tokyo, 150-8308, Japan

    Hiroshi Takami

  2. , Department of Surgery, Kuma Hospital, 8-2-35 Shimoyamate-dori, Chuo-ku, Kobe, 650-0011, Japan

    Yasuhiro Ito

  3. Noguchi Thyroid Clinic and Hospital Foun, 6-33 Noguchinaka-machi, Beppu, 874-0932, Japan

    Hitoshi Noguchi

  4. , Department of Breast and Endocrine Surge, Kanagawa Cancer Center, 1-1-2 Nakao, Asahi-ku, Yokohama, 241-8515, Japan

    Akira Yoshida

  5. , Department of Endocrine Surgery, Tokyo Women's Medical University, 8-1 Kawada- cho, Shinjuku-ku, Tokyo, 162-8666, Japan

    Takahiro Okamoto

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer Japan

About this chapter

Cite this chapter

Saikawa, M., Akasu, H. (2013). Column 3. Anaplastic Transformation of Differentiated Carcinoma. In: Takami, H., Ito, Y., Noguchi, H., Yoshida, A., Okamoto, T. (eds) Treatment of Thyroid Tumor. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54049-6_6

Download citation

  • DOI: https://doi.org/10.1007/978-4-431-54049-6_6

  • Published:

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-54048-9

  • Online ISBN: 978-4-431-54049-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation