CQ18. Does Central Compartment Dissection Improve the Prognosis of Papillary Carcinoma Patients?

  • Tsuneo Imai
  • Hiroya Kitano
  • Iwao Sugitani
  • Nobuyuki Wada


Central node dissection is recommended for patients with lymph node swelling suspected of metastasis. However, it remains unclear whether the central compartment should be dissected for patients without obvious swollen lymph nodes on imaging studies such as ultrasonography. There are reports demonstrating that central node dissection improves patient prognosis, while studies presenting not only negative findings for the improvement in prognosis, but also an increase in risks of complications such as hypoparathyroidism and recurrent laryngeal nerve paralysis have also been published. In this chapter, the discussion is on whether central node dissection reflects prognosis of patients with papillary carcinoma.


Papillary Carcinoma Central Compartment Recurrent Laryngeal Nerve Paralysis Central Node Metastasis Central Node Dissection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Tisell LE, Nilsson B, Mölne J et al (1996) Improved survival of patients with papillary thyroid cancer after surgical microdissection. World J Surg 20:854–859 (PS)PubMedCrossRefGoogle Scholar
  2. 2.
    Scheumann GF, Gimm O, Wegener G et al (1994) Prognostic significance and surgical management of locoresional lymph node metastases in papillary thyroid cancer. World J Surg 18:559–567 (RS)PubMedCrossRefGoogle Scholar
  3. 3.
    Simon D, Goretzki PE, Witte J et al (1996) Incidence of regional recurrence guiding radicality in differentiated thyroid carcinoma. World J Surg 20:860–866 (RS)PubMedCrossRefGoogle Scholar
  4. 4.
    Ito Y, Jikuzono T, Higashiyama T et al (2006) Clinical significance of lymph node metastasis of thyroid papillary carcinoma located in one. World J Surg 30:1821–1828 (RS)PubMedCrossRefGoogle Scholar
  5. 5.
    Wada N, Duh QY, Sugino K et al (2003) Lymph node metastasis from 259 papillary thyroid microcarcinomas: frequency, pattern of occurrence and recurrence, and optimal strategy for neck dissection. Ann Surg 237:399–407 (RS)PubMedGoogle Scholar
  6. 6.
    Shah MD, Hall FT, Eski SJ et al (2003) Clinical course of thyroid carcinoma after neck dissection. Laryngoscope 113:2102–2107 (RS)PubMedCrossRefGoogle Scholar
  7. 7.
    White ML, Gauger PG, Doherty GM (2007) Central lymph node dissection in differentiated thyroid cancer. World J Surg 31:895–904 (RS)PubMedCrossRefGoogle Scholar
  8. 8.
    Sato N, Oyamatsu M, Koyama Y et al (1998) Do the level of nodal disease according to the TNM classification and the number of involved cervical nodes reflect prognosis in patients with differentiated carcinoma of the thyroid gland? J Surg Oncol 69:151–155 (RS)PubMedCrossRefGoogle Scholar
  9. 9.
    Pereira JA, Jimeno J, Miquel J et al (2005) Nodal yield, morbidity, and recurrence after central neck dissection for papillary thyroid carcinoma. Surgery 138:1095–1100 (RS)PubMedCrossRefGoogle Scholar
  10. 10.
    British Thyroid Association and Royal College of Physicians (2007) Guidelines for the management of thyroid cancer, 2nd edn. vol 15. The Lavenham Press, Suffolk (Others)Google Scholar

Copyright information

© Springer Japan 2013

Authors and Affiliations

  • Tsuneo Imai
    • 1
  • Hiroya Kitano
    • 2
  • Iwao Sugitani
    • 3
  • Nobuyuki Wada
    • 4
  1. 1.Department of Breast & Endocrine SurgeryNagoya UniversityNagoyaJapan
  2. 2.Division of Otolaryngology, Head & Neck Surgery, Department of Sensory and Motor Organ, Faculty of MedicineTottori UniversityTottoriJapan
  3. 3.Division of Head and NeckCancer Institute Hospital, Japanese Foundation for Cancer ResearchTokyoJapan
  4. 4.Department of SurgeryYokohama City UniversityYokohamaJapan

Personalised recommendations