Total Synthesis through Palladium-Catalyzed Bis-Cyclization of Bromoallenes

  • Shinsuke Inuki
Part of the Springer Theses book series (Springer Theses)


Palladium(0)-catalyzed cyclization of bromoallenes bearing hydroxy and benzamide groups as internal nucleophiles stereoselectively provides functionalized tetrahydrofuran. This cyclization was expanded to divergent synthesis of pachastrissamine, a biologically active marine natural product, and its derivatives.


Flash Chromatography Grignard Reagent Alkyl Side Chain Intermolecular Reaction Bicyclic Compound 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer 2012

Authors and Affiliations

  1. 1.Graduate School of Pharmaceutical SciencesKyoto UniversityKyotoJapan

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