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Prism Adaptation and the Rehabilitation of Spatial Neglect

  • Sophie Jacquin-Ciourtois
  • Jacinta O’Shea
  • Jacques Luauté
  • Laure Pisella
  • Alessandro Farné
  • Patrice Revol
  • Gilles Rode
  • Yves Rossetti

Abstract

A large proportion of right-hemisphere stroke patients exhibits spatial neglect, a neurological condition characterised by deficits for perceiving, attending, representing, and/or performing actions within their left-sided space. spatial neglect is responsible for many debilitating effects on everyday life, for poor functional recovery, and for decreased ability to benefit from treatment. Prism adaptation (PA) to a right lateral displacement of the visual field (induced by a simple target-pointing task while wearing base-left wedge prisms) is known to directionally bias visuo-motor and sensory-motor correspondences and has recently been found to improve various symptoms of neglect. For example, performance on classical pen-and-pencil visuo-motor tests could be improved for at least 2 h following adaptation. Further effects of PA have also been described for non-motor and non-visual tasks, such as for somatosensory extinction or dichotic listening, for deficits in mental imagery of geographic maps and in number bisection, and even for visuo-constructive disorders. These results suggest that the effects of prism adaptation can extend to unexposed sensory systems. The bottom-up approach of visuo-motor adaptation appears to interact with higher order brain functions related to multisensory integration and can have beneficial effects on sensory processing in different modalities. Lesion studies and functional imaging data point to a cerebello-cortical network in which the cerebellum is crucial for adaptation and the cortex is involved in functional gains. Prism adaptation may act not only on the ipsilesional bias characteristic of neglect and also alleviate more generally other spatial cognition deficits due to attentional bias.

Keywords

Complex Regional Pain Syndrome Multisensory Integration Neglect Patient Spatial Neglect Visuomotor Adaptation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer 2011

Authors and Affiliations

  • Sophie Jacquin-Ciourtois
    • 1
    • 2
    • 3
  • Jacinta O’Shea
    • 4
  • Jacques Luauté
    • 1
    • 2
    • 3
  • Laure Pisella
    • 1
    • 2
  • Alessandro Farné
    • 1
    • 2
  • Patrice Revol
    • 1
    • 2
    • 3
  • Gilles Rode
    • 1
    • 2
    • 3
  • Yves Rossetti
    • 1
    • 2
    • 3
  1. 1.Centre de recherche en Neurosciences de Lyon, Inserm U1028, CRNS UMR5092BronFrance
  2. 2.Université de Lyon, Université Lyon 1LyonFrance
  3. 3.Service de Rééducation Neurologique, Plate-forme Mouvement et HandicapHôpital Henry Gabrielle, Hospices Civils de LyonSt Genis LavalFrance
  4. 4.Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB), Nuffield Department of Clinical NeurosciencesUniversity of OxfordOxfordUK

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