Brain Hypothermia for Occlusive Cerebral Stroke
The mechanism of brain damage caused by occlusive cerebral stroke is different with acute onset and chronic progression. The harmful stress-associated neurohormonal reactions of the hypothalamus—pituitary—adrenal (HPA) axis and hyperglycemia [8, 9, 10] are only observed at the acute onset of large cerebral infarction (Table 82.) In this group, a higher incidence of complete cerebrovascular obstruction (CVO) than incomplete CVO was recorded. However, in cases of slow onset, incomplete occlusive cerebral stroke or small cerebral infarction are most common and stress-associated hyperglycemia is not recorded. The intensive care unit (ICU) management strategy is different in these two groups.
KeywordsCerebral Infarction Slow Onset Brain Stem Infarction Selective Brain Cool Brain Hypothermia
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- 6.Dorman PJ, Counsell CE, Sanderrock PGA (2000) Recently developed neuroprotective therapies for acute stroke: a qualitative systematic review of clinical trials. In: Prakash A (ed) Acute stroke treatment. Adis, Hong Kong, pp 63–83Google Scholar
- 8.Hayashi N (1997) Prevention of vegetation after severe head trauma and stroke by combination therapy of cerebral hypothermia and activation of immune-dopaminergic nervous system. Proc Soc Treat Coma 6:133–145Google Scholar
- 11.Lindley RI (2000) Drug therapy for acute ischemic stroke: risks verusus benefits. In: Prakash A (ed) Acute stroke treatment. Adis, Hong Kong, pp 53–62Google Scholar