Noninvasive Monitoring of Brain Damage
The monitoring of brain tissue temperature, intracranial pressure (ICP), SjO2, oxygen delivery, and cerebral perfusion pressure (CPP) is necessary in intensive care unit (ICU) brain hypothermia management as fundamentals of the technique [1,8]. However, these monitors require considerable skill, are invasive to critically ill patients, and are difficult to perform in the early part of the acute stage. In addition, information about the severity of the catecholamine surge, blood-brain barrier (BBB) dysfunction, cerebral blood flow (CBF) disturbances, microcirculatory disturbances, brain metabolism and release of neurotoxic amino acids are useful to ICU brain hypothermia management [1,8]. However, these monitors cannot always be used because of practical limitations that include small medical teams at night, no monitoring system for the microdialysis technique, no high-speed liquid chromatography, limited insurance cover for brain hypothermia management, and limited economic support of these advanced monitors . In addition, we have no times to monitors by abruptly rapid fall to critical conditions.
KeywordsCerebral Blood Flow Albumin Ratio Indirect Parameter Carotid Blood Flow Tympanic Membrane Temperature
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