Preparation for Management of Brain Hypothermia
Stabilized systemic circulation and cardiac function is important from the beginning of treatment because serum catecholamines progressively decrease in proportion to the severity of brain tissue hypothermia . Early dehydration management to prevent brain edema introduces difficult conditions for the induction of brain hypothermia treatment because of reduced systemic circulation volume and unstable cardiac output. An arrhythmia-prolonged QT-interval of more than 450 mm/s, hyperglycemia, and hypopotassemia must be controlled before the induction of hypothermia. The complication of severe pneumonia produces unsuccessful brain hypothermia because of uncontrollable increases in brain tissue glutamate associated with cytokine encephalitis. To prevent pneumonia (Mendelson’s syndrome), food and gastric juice in the stomach should be washed out by gastric lavage with 1000 ml of cooled saline, immune function should be managed by maintaining microcirculation of the intestinal organs by replacement of antithrombin III (AT-III) to above the 100% level, intestinal mucous membrane edema can be prevented by management of serum albumin levels above 3.0g/dl, and serum glucose levels should be carefully maintained between 120 and 140 mg/dl [1, 2, 3].
KeywordsOsmotic Dehydration Gastric Lavage Brain Injured Patient Hypothermia Treatment Auditory Brainstem Evoke Response
Unable to display preview. Download preview PDF.
- 1.Hayashi N (1995) Cerebral hypothermia treatment. In: Hayashi N (ed) Cerebral hypothermia treatment. Sogo Igaku, Tokyo, pp 1–105Google Scholar