Abstract
The main targets of brain hypothermia treatment are the adequate administration of oxygen, control of metabolic substrates, prevention of hypothalamuspituitary- adrenal (HPA) axis neurohormonal brain damage, and exclusion of selective neuronal damage to the dopamine A10 nervous system by controlling the brain tissue temperature to 32°–34°C [5–7]. The fundamental plan for brain hypothermia treatment is summarized in Fig. 39. After treatment, additional cerebral dopamine replacement therapy is followed to prevent memory disturbance and vegetation [4,5,7].
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References
Bioch M (1967) Cerebral effects of rewarming following prolonged hypothermia: significance for the management of severe cranio-cerebral injury and acute pyrexia. Brain 90:769–784
Corte FD, Mancini A, Valle D, Gallizzi F, Carducci P, Mignani V, De Marinis L (1998) Provocative hypothalamopituitary axis tests in severe head injury: correlation with severity and prognosis. Crit Care Med 26:1419–1426
Hayashi N (1995) Cerebral hypothermia treatment. In: Hayashi N (ed) Cerebral hypothermia treatment. Sogo Igaku Tokyo, pp 1–105
Hayashi N (1997) Combination therapy of cerebral hypothermia, pharmacological activation of the dopamine system, and hormonal replacement in severely brain damaged patients. J Jpn Intensive Care Med 4:191–197
Hayashi N (1997) Prevention of vegetation after severe head trauma and stroke by combination therapy of cerebral hypothermia and activation of immunedopaminergic nervous system. Proceedings of the 6th annual meeting of Society for Treatment of Coma 6: 133–145
Hayashi N (2000) Enhanced neuronal damage in severely brain injured patients by hypothalamus, pituitary, and adrenal axis neuro-hormonal changes. In: Hayashi N (ed) Brain hypothermia. Springer Berlin Heidelberg New York Tokyo, pp 3–26
Hayashi N (2000) The clinical issue and effectiveness of brain hypothermia treatment for severe brain injured patients. In: Hayashi N (ed) Brain hypothermia. Springer, Berlin Heidelberg New York Tokyo, pp 121–151
Hayashi N, Hirayama T, Utagawa T, Ohata M (1994) Systemic management of cerebral edema based on a new concept in severe head injury patients. Acta Neurochir 60:541–543
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© 2004 Springer Japan
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Hayashi, N., Dietrich, D.W. (2004). The Protocol for Brain Hypothermia Treatment. In: Brain Hypothermia Treatment. Springer, Tokyo. https://doi.org/10.1007/978-4-431-53953-7_34
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DOI: https://doi.org/10.1007/978-4-431-53953-7_34
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-67964-6
Online ISBN: 978-4-431-53953-7
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