Therapeutic Hypothermia in Complicated Models of Traumatic Brain Injury
Clinical and experimental data emphasize the importance of secondary injury mechanisms contributing to traumatic outcome [1, 2, 3, 4,8]. Secondary injury mechanisms include a variety of systemic and intracranial processes including hypotension, hypoxia, ischemia, and hyperthermia, as well as intra cranial pressure. Secondary hypoxia caused by respiratory distress is a common consequence of head injury. It has been reported to occur in 45.6% of severely head-injured patients.
KeywordsTraumatic Brain Injury Therapeutic Hypothermia Control Cortical Impact Intra Cranial Pressure Contusion Volume
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