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Adult Neurogenesis in Reptiles

  • Chapter
Neurogenesis in the Adult Brain I

Abstract

Adult neurogenesis in reptiles is a well-documented phenomenon and exists in many telencephalic areas. The newly generated neurons originate along the walls of the lateral ventricles, mainly in the sulci. The putative neural progenitors are radial glial cells. These glial cells give rise to neuroblasts that migrate to their final destination. In general, the new neurons are born in the portion of the ventricular zone (VZ) adjacent to the telencephalic area where they will be recruited and migrate radially through the brain parenchyma along the processes of radial glial cells to their final destination, although migration to the olfactory bulbs (OB) is different. Specifically, it seems that new neurons of the OB are not produced in the ventricular walls of the OB ventricle, but instead in more caudal levels of the lateral ventricles. They then migrate tangentially over the soma of the VZ radial glia until they reach the OB. Adult neurogenesis creates microneurons and projection neurons, and occasionally there is gliogenesis as well.

One last striking feature of the reptilian brain is their ability to regenerate large neuronal populations that have died as a result of physical and chemical injuries.

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Abbreviations

3AP:

3-Acetylpyridine

3HT:

Tritiated thymidine

ADVR:

Anterior dorsal ventricular ridge

AOB:

Accesory olfactory bulb

AON:

Anterior olfactory nucleus

BrdU:

Bromodeoxyuridine

CNS:

Central nervous system

CRMP-4:

Collapsin response-mediated protein 4

DC:

Dorsal cortex

DMC:

Dorsomedial cortex

DVR:

Dorsal ventricular ridge

GFAP:

Glial fibrillary acidic protein

LC:

Lateral cortex

MC:

Medial cortex

MOB:

Main olfactory bulb

NS:

Nucleus sphericus

OB:

Olfactory bulb

PSA-NCAM:

Polysialic neural cell adhesion molecule

sl:

Sulcus lateralis

SP:

Septum

ssm:

Sulcus septomedialis

st:

Sulcus terminalis

ST:

Striatum

sv:

Sulcus ventralis

SVZ:

Subventricular zone

VZ:

Ventricular zone

References

  • Ahboucha S, Laalaoui A, Didier-Bazes M, Montange M, Cooper HM, Gamrani H (2003) Differential patterns of glial fibrillary acidic protein-immunolabeling in the brain of adult lizards. J Comp Neurol 464:159–171.

    Article  PubMed  Google Scholar 

  • Alibardi L (1994) H3-thymidine labeled cerebrospinal fluid contacting cells in the regenerating caudal spinal cord of the lizard Lampropholis. Ann Anat 176:347–356.

    Article  PubMed  CAS  Google Scholar 

  • Alvarez-Buylla A (1990) Mechanism of neurogenesis in adult avian brain. Experientia 46:948–955.

    Article  CAS  Google Scholar 

  • Alvarez-Buylla A, Theelen M, Nottebohm F (1990) Proliferation “hot spots” in adult avian ventricular zone reveal radial cell division. Neuron 5:101–109.

    Article  PubMed  CAS  Google Scholar 

  • Alvarez-Buylla A, Garcia-Verdugo JM, Mateo AS, Merchant-Larios H (1998) Primary neural precursors and intermitotic nuclear migration in the ventricular zone of adult canaries. J Neurosci 18:1020–1037.

    PubMed  CAS  Google Scholar 

  • Austin CP, Cepko CL (1990) Cellular migration patterns in the developing mouse cerebral cortex. Development 110:713–732.

    CAS  Google Scholar 

  • Beazley LD, Sheard PW, Tennant M, Starac D, Dunlop SA (1997) Optic nerve regenerates but does not restore topographic projections in the lizard Ctenophorus ornatus. J Comp Neurol 377:105–120.

    Article  PubMed  CAS  Google Scholar 

  • Bruce LL, Neary TJ (1995) The limbic system of tetrapods: a comparative analysis of cortical and amygdalar populations. Brain Behav Evol 46:224–234.

    Article  PubMed  CAS  Google Scholar 

  • Butler AB, Hodos W (1996) Comparative vertebrate neuroanatomy: Evolution and adaptation. Wiley-Liss, New York.

    Google Scholar 

  • Chernoff EA (1996) Spinal cord regeneration: a phenomenon unique to urodeles? Int J Dev Biol 40:823–831.

    PubMed  CAS  Google Scholar 

  • Davila JC, Guirado S, De la Calle A, Marin-Giron F (1985) Electron microscopy of the medial cortex in the lizard Psammodromus algirus. J Morphol 185:327–338.

    Article  Google Scholar 

  • Del Grande P, Franceschini V, Minelli G, Ciani F (1990) Mitotic activity of the telencephalic matrix areas following optic tectum or pallial cortex lesion in newt. Z Mikrosk Anat Forsch 104:617–624.

    PubMed  Google Scholar 

  • Delgado-Gonzalez FJ, Alonso-Fuentes A, Delgado-Fumero A, Garcia-Verdugo JM, Gonzalez-Granero S, Trujillo-Trujillo CM, Damas-Hernandez MC (2008) Seasonal differences in ventricular proliferation of adult Gallotia galloti lizards. Brain Res 1191:39–46.

    Article  PubMed  CAS  Google Scholar 

  • Desfilis E, Garcia-Verdugo JM, Font E (1993) Regeneration in the adult lizard brain: further evidence from 3TH autoradiography. Eur J Neurosci S6:290.

    Google Scholar 

  • Doetsch F, Garcia-Verdugo JM, Alvarez-Buylla A (1997) Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J Neurosci 17:5046–5061.

    PubMed  CAS  Google Scholar 

  • Doetsch F, Caille I, Lim DA, Garcia-Verdugo JM, Alvarez-Buylla A (1999) Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97:703–716.

    Article  PubMed  CAS  Google Scholar 

  • Duffy MT, Simpson SB, Liebich DR, Davis BM (1990) Origin of spinal cord axons in the lizard regenerated tail: supernormal projections from local spinal neurons. J Comp Neurol 293:208–222.

    Article  PubMed  CAS  Google Scholar 

  • Duffy MT, Liebich DR, Garner LK, Hawrych A, Simpson SB, Jr., Davis BM (1992) Axonal sprouting and frank regeneration in the lizard tail spinal cord: correlation between changes in synaptic circuitry and axonal growth. J Comp Neurol 316:363–374.

    Article  PubMed  CAS  Google Scholar 

  • Font E, Garcia-Verdugo JM, Alcantara S, Lopez-Garcia C (1991) Neuron regeneration reverses 3-acetylpyridine-induced cell loss in the cerebral cortex of adult lizards. Brain Res 551:230–235.

    Article  PubMed  CAS  Google Scholar 

  • Font C, Hoogland PV, Vermeulen van der Zee E, Perez-Clausell J, Martinez-Garcia F (1995a) The septal complex of the telencephalon of the lizard Podarcis hispanica. I. Chemoarchitectonical organization. J Comp Neurol 359:117–130.

    Article  PubMed  CAS  Google Scholar 

  • Font E, Garcia-Verdugo JM, Desfilis E, Perez-Cañellas M (1995b) Neuron-glia interrelations during 3-acetylpyridine-induced degeneration and regeneration in the adult lizard brain. In: Vernadakis A, Roots B (eds) Neuron-glia interrelations during phylogeny: II. Plasticity and regeneration. Humana press Inc, Totowa.

    Google Scholar 

  • Font E, Desfilis E, Perez-Cañellas M, Alcantara S, Garcia-Verdugo JM (1997) 3-Acetylpyridine-induced degeneration and regeneration in the adult lizard brain: a qualitative and quantitative analysis. Brain Res 754:245–259.

    Article  PubMed  CAS  Google Scholar 

  • Font E, Desfilis E, Perez-Cañellas MM, Garcia-Verdugo JM (2001) Neurogenesis and neuronal regeneration in the adult reptilian brain. Brain Behav Evol 58:276–295.

    Article  PubMed  CAS  Google Scholar 

  • Garcia-Verdugo JM, Berbel PJ, Lopez-Garcia C (1981) [Golgi and electron microscopy study of cerebral ependymocytes of the lizard Lacerta galloti]. Trab Inst Cajal 72:269–278.

    PubMed  CAS  Google Scholar 

  • Garcia-Verdugo JM, Berbel-Navarro P, Regidor-Garcia J, Lopez-Garcia C (1984) Ultrastructure of neuronal cell bodies in the medial cortex of Lacerta galloti. J Hirnforsch 25:187–196.

    PubMed  CAS  Google Scholar 

  • Garcia-Verdugo JM, Fariñas I, Molowny A, Lopez-Garcia C (1986a) Ultrastructure of putative migrating cells in the cerebral cortex of Lacerta galloti. J Morphol 189:189–197.

    Article  PubMed  CAS  Google Scholar 

  • Garcia-Verdugo JM, Llahi S, Fariñas I, Martin V (1986b) Laminar organization of the main olfactory bulb of Podarcis hispanica: an electron microscopic and Golgi study. J Hirnforsch 27:87–100.

    PubMed  CAS  Google Scholar 

  • Garcia-Verdugo JM, Llahi S, Ferrer I, Lopez-Garcia C (1989) Postnatal neurogenesis in the olfactory bulbs of a lizard. A tritiated thymidine autoradiographic study. Neurosci Lett 98:247–252.

    Article  PubMed  CAS  Google Scholar 

  • Garcia-Verdugo JM, Ferron S, Flames N, Collado L, Desfilis E, Font E (2002) The proliferative ventricular zone in adult vertebrates: a comparative study using reptiles, birds, and mammals. Brain Res Bull 57:765–775.

    Article  PubMed  Google Scholar 

  • Goffinet AM, Daumerie C, Langerwerf B, Pieau C (1986) Neurogenesis in reptilian cortical structures: 3H-thymidine autoradiographic analysis. J Comp Neurol 243:106–116.

    Article  PubMed  CAS  Google Scholar 

  • Gould E, Tanapat P (1997) Lesion-induced proliferation of neuronal progenitors in the dentate gyrus of the adult rat. Neuroscience 80:427–436.

    Article  PubMed  CAS  Google Scholar 

  • Gould E, Tanapat P (1999) Stress and hippocampal neurogenesis. Biol Psychiatry 46:1472–1479.

    Article  PubMed  CAS  Google Scholar 

  • Holtzman DA (1993) The ontogeny of nasal chemical senses in garter snakes. Brain Behav Evol 41:163–170.

    Article  PubMed  CAS  Google Scholar 

  • Holtzman DA, Halpern M (1991) Incorporation of 3H-thymidine in telencephalic structures of the vomeronasal and olfactory systems of embryonic garter snakes. J Comp Neurol 304:450–466.

    Article  PubMed  CAS  Google Scholar 

  • Hoogland PV, Vermeulen-Vanderzee E (1995) Efferent connections of the lateral cortex of the lizard Gekko gecko: evidence for separate origins of medial and lateral pathways from the lateral cortex to the hypothalamus. J Comp Neurol 352:469–480.

    Article  PubMed  CAS  Google Scholar 

  • Hulsebosch CE, Bittner GD (1980) Evolution of abilities to regenerate neurons in central nervous system. Am Nat 115:276–284.

    Article  Google Scholar 

  • Johnston JB (1916) Evidence of a motor pallium in the forebrain of reptiles. J Comp Neurol 26:469–480.

    Google Scholar 

  • Kempermann G (2006) Adult neurogenesis: stem cells and neuronal development in the adult brain. Oxford, New York.

    Google Scholar 

  • Kirsche W (1983) The significance of matrix zones for brain regeneration and brain transplantation with special consideration of lower vertebrates. In: Wallace RB, Das GD (eds) Neural tissue transplantation research. Springer, Berlin.

    Google Scholar 

  • Lang DM, Monzon-Mayor M, Bandtlow CE, Stuermer CA (1998) Retinal axon regeneration in the lizard Gallotia galloti in the presence of CNS myelin and oligodendrocytes. Glia 23:61–74.

    Article  PubMed  CAS  Google Scholar 

  • Lang DM, Romero-Aleman MM, Arbelo-Galvan JF, Stuermer CA, Monzon-Mayor M (2002) Regeneration of retinal axons in the lizard Gallotia galloti is not linked to generation of new retinal ganglion cells. J Neurobiol 52:322–335.

    Article  PubMed  Google Scholar 

  • Lois C, Alvarez-Buylla A (1994) Long-distance neuronal migration in the adult mammalian brain. Science 264:1145–1148.

    Article  PubMed  CAS  Google Scholar 

  • Lopez-Garcia C (1993) Postnatal neurogenesis and regeneration in the lizard cerebral cortex. In: Cuello AC (ed) Restorative neurology. Elsevier, Amsterdam.

    Google Scholar 

  • Lopez-Garcia C, Martinez-Guijarro FJ (1988) Neurons in the medial cortex give rise to Timm-positive boutons in the cerebral cortex of lizards. Brain Res 463:205–217.

    Article  PubMed  CAS  Google Scholar 

  • Lopez-Garcia C, Tineo PL, Del Corral J (1984) Increase of the neuron number in some cerebral cortical areas of a lizard, Podarcis hispanica, (Steind., 1870), during postnatal periods of life. J Hirnforsch 25:255–259.

    Google Scholar 

  • Lopez-Garcia C, Molowny A, Garcia-Verdugo JM, Ferrer I (1988a) Delayed postnatal neurogenesis in the cerebral cortex of lizards. Brain Res 471:167–174.

    PubMed  CAS  Google Scholar 

  • Lopez-Garcia C, Molowny A, Rodriguez-Serna R, Garcia Verdugo JM, Martinez-Guijarro FJ (1988b) Postnatal development of neurons in the telencephalic cortex of lizards. In: Schwerdtfeger WK, Smeets WJAJ (eds) The forebrain of reptiles: Current concepts of structure and function. Karger, Basel.

    Google Scholar 

  • Lopez-Garcia C, Molowny A, Garcia-Verdugo JM, Martinez-Guijarro FJ, Bernabeu A (1990a) Late generated neurons in the medial cortex of adult lizards send axons that reach the Timm-reactive zones. Brain Res Dev Brain Res 57:249–254.

    Article  PubMed  CAS  Google Scholar 

  • Lopez-Garcia C, Molowny A, Garcia-Verdugo JM, Perez-Sanchez F, Martinez-Guijarro FJ (1990b) Postnatal neurogenesis in the brain of the lizard Podarcis hispanica. In: Schwerdtfeger WK, Germroth P (eds) The forebrain in nonmammals: New aspects of structure and development. Springer, Berlin.

    Google Scholar 

  • Lopez-Garcia C, Molowny A, Martinez-Guijarro FJ, Blasco-Ibanez JM, Luis de la Iglesia JA, Bernabeu A, Garcia-Verdugo JM (1992) Lesion and regeneration in the medial cerebral cortex of lizards. Histol Histopathol 7:725–746.

    PubMed  CAS  Google Scholar 

  • Lopez-Garcia C, Nacher J, Castellano B, Luis de la Iglesia JA, Molowny A (1994) Transitory disappearance of microglia during the regeneration of the lizard medial cortex. Glia 12:52–61.

    Article  PubMed  CAS  Google Scholar 

  • Luis de la Iglesia JA, Lopez-Garcia C (1997a) A Golgi study of the short-axon interneurons of the cell layer and inner plexiform layer of the medial cortex of the lizard Podarcis hispanica. J Comp Neurol 385:565–598.

    Article  PubMed  CAS  Google Scholar 

  • Luis de la Iglesia JA, Lopez-Garcia C (1997b) A Golgi study of the principal projection neurons of the medial cortex of the lizard Podarcis hispanica. J Comp Neurol 385:528–564.

    Article  PubMed  CAS  Google Scholar 

  • Marchioro M, Nunes JM, Ramalho AM, Molowny A, Perez-Martinez E, Ponsoda X, Lopez-Garcia C (2005) Postnatal neurogenesis in the medial cortex of the tropical lizard Tropidurus hispidus. Neuroscience 134:407–413.

    Article  PubMed  CAS  Google Scholar 

  • Margotta V, Morelli A (1996) Encephalic matrix areas and post-natal neurogenesis under natural and experimental conditions. Anim Biol 5:117–131.

    Google Scholar 

  • Martinez-Garcia F, Amiguet M, Olucha F, Lopez-Garcia C (1986) Connections of the lateral cortex in the lizard Podarcis hispanica. Neurosci Lett 63:39–44.

    Article  PubMed  CAS  Google Scholar 

  • Martinez-Garcia F, Amiguet M, Schwerdfeger WK (1990) Interhemispheric connections through the pallial commissures in the brain of Podarcis hispanica and Gallotia-Stehlinii (Reptilia, Lacertidae). J Morphol 205:17–31.

    Google Scholar 

  • Martinez-Garcia F, Martinez-Marcos A, Lanuza E (2002) The pallial amygdala of amniote vertebrates: evolution of the concept, evolution of the structure. Brain Res Bull 57:463–469.

    Article  PubMed  Google Scholar 

  • Martinez-Guijarro FJ, Soriano E, Del Rio JA, Lopez-Garcia C (1991) Zinc-positive boutons in the cerebral cortex of lizards show glutamate immunoreactivity. J Neurocytol 20:834–843.

    Article  PubMed  CAS  Google Scholar 

  • Minelli G, del Grande P, Mambelli MC (1977) Preliminary study of the regenerative processes of the dorsal cortex of the telencephalon of Lacerta viridis. Z Mikrosk Anat Forsch 91:241–256.

    PubMed  CAS  Google Scholar 

  • Minelli G, Franceschini V, Del Grande P, Ciani F (1987) Newly-formed neurons in the regenerating optic tectum of Triturus cristatus carnifex. Basic Appl Histochem 31:43–52.

    PubMed  CAS  Google Scholar 

  • Molowny A, Nacher J, Lopez-Garcia C (1995) Reactive neurogenesis during regeneration of the lesioned medial cerebral cortex of lizards. Neuroscience 68:823–836.

    Article  PubMed  CAS  Google Scholar 

  • Monzon-Mayor M, Yanes C, Tholey G, De Barry J, Gombos G (1990) Immunohistochemical localization of glutamine synthetase in mesencephalon and telencephalon of the lizard Gallotia galloti during ontogeny. Glia 3:81–97.

    Article  PubMed  CAS  Google Scholar 

  • Nacher J, Ramirez C, Palop JJ, Molowny A, Luis de la Iglesia JA, Lopez-Garcia C (1999a) Radial glia and cell debris removal during lesion-regeneration of the lizard medial cortex. Histol Histopathol 14:89–101.

    PubMed  CAS  Google Scholar 

  • Nacher J, Ramirez C, Palop JJ, Artal P, Molowny A, Lopez-Garcia C (1999b) Microglial cells during the lesion-regeneration of the lizard medial cortex. Histol Histopathol 14:103–117.

    PubMed  CAS  Google Scholar 

  • Nacher J, Soriano S, Varea E, Molowny A, Ponsoda X, Lopez-Garcia C (2002) CRMP-4 expression in the adult cerebral cortex and other telencephalic areas of the lizard Podarcis hispanica. Brain Res Dev Brain Res 139:285–294.

    Article  PubMed  CAS  Google Scholar 

  • O’Rourke NA, Sullivan DP, Kaznowski CE, Jacobs AA, McConnell SK (1995) Tangential migration of neurons in the developing cerebral cortex. Development 121:2165–2176.

    Google Scholar 

  • Peñafiel A, Gutierrez A, Martin R, Perez-Cañellas MM, de la Calle A (1996) A tangential neuronal migration in the olfactory bulbs of adult lizards. Neuroreport 7:1257–1260.

    Article  PubMed  Google Scholar 

  • Perez-Cañellas MM, Garcia-Verdugo JM (1996) Adult neurogenesis in the telencephalon of a lizard: a [3H]thymidine autoradiographic and bromodeoxyuridine immunocytochemical study. Brain Res Dev Brain Res 93:49–61.

    Article  PubMed  Google Scholar 

  • Perez-Cañellas MM, Font E, Garcia-Verdugo JM (1997) Postnatal neurogenesis in the telencephalon of turtles: evidence for nonradial migration of new neurons from distant proliferative ventricular zones to the olfactory bulbs. Brain Res Dev Brain Res 101:125–137.

    Article  PubMed  Google Scholar 

  • Perez-Sanchez F, Molowny A, Garcia-Verdugo JM, Lopez-Garcia C (1989) Postnatal neurogenesis in the nucleus sphericus of the lizard, Podarcis hispanica. Neurosci Lett 106:71–75.

    Article  PubMed  CAS  Google Scholar 

  • Rakic P (1971) Guidance of neurons migrating to the fetal monkey neocortex. Brain Res 33:471–476.

    Article  PubMed  CAS  Google Scholar 

  • Ramirez C, Nacher J, Molowny A, Sanchez-Sanchez F, Irurzun A, Lopez-Garcia C (1997) Photoperiod-temperature and neuroblast proliferation-migration in the adult lizard cortex. Neuroreport 8:2337–2342.

    Article  PubMed  CAS  Google Scholar 

  • Ramirez-Castillejo C, Nacher J, Molowny A, Ponsoda X, Lopez-Garcia C (2002) PSA-NCAM immunocytochemistry in the cerebral cortex and other telencephalic areas of the lizard Podarcis hispanica: differential expression during medial cortex neuronal regeneration. J Comp Neurol 453:145–156.

    Article  PubMed  Google Scholar 

  • Romero-Aleman MM, Monzon-Mayor M, Yanes C, Lang D (2004) Radial glial cells, proliferating periventricular cells, and microglia might contribute to successful structural repair in the cerebral cortex of the lizard Gallotia galloti. Exp Neurol 188:74–85.

    Article  PubMed  CAS  Google Scholar 

  • Scharff C, Kirn JR, Grossman M, Macklis JD, Nottebohm F (2000) Targeted neuronal death affects neuronal replacement and vocal behavior in adult songbirds. Neuron 25:481–492.

    Article  PubMed  CAS  Google Scholar 

  • Seri B, Garcia-Verdugo JM, McEwen BS, Alvarez-Buylla A (2001) Astrocytes give rise to new neurons in the adult mammalian hippocampus. J Neurosci 21:7153–7160.

    PubMed  CAS  Google Scholar 

  • Simpson SB, Jr., Duffy MT (1994) The lizard spinal cord: a model system for the study of spinal cord injury and repair. Prog Brain Res 103:229–241.

    Article  PubMed  Google Scholar 

  • Stensaas LJ, Stensaas SS (1968) Light microscopy of glial cells in turtles and birds. Z Zellforsch Mikrosk Anat 91:315–340.

    Article  PubMed  CAS  Google Scholar 

  • Striedter GF (1997) The telencephalon of tetrapods in evolution. Brain Behav Evol 49:179–213.

    Article  PubMed  CAS  Google Scholar 

  • Tineo PL, Planelles MD, Del-Corral J (1987) Modifications in cortical ependyma of the lizard, Podarcis hispanica, during postnatal development. J Hirnforsch 28:485–489.

    PubMed  CAS  Google Scholar 

  • Ulinski PS (1990) The cerebral cortex of reptiles. In: Jones EG, Peters A (eds) Cerebral cortex. Plenum, New York.

    Google Scholar 

  • Ulinski PS, Kanarek DA (1973) Cytoarchitecture of nucleus sphericus in the common boa, Constrictor constrictor. J Comp Neurol 151:159–174.

    Article  PubMed  CAS  Google Scholar 

  • Yanes-Mendez C, Martin-Trujillo JM, Perez-Batista MA, Mozon-Mayor M, Marrero A (1988) Ependymogenesis of the lizard basal areas. I. Ependymal zones. Z Mikrosk Anat Forsch 102:555–572.

    Google Scholar 

  • Zupanc GK, Ott R (1999) Cell proliferation after lesions in the cerebellum of adult teleost fish: time course, origin, and type of new cells produced. Exp Neurol 160:78–87.

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

Special thanks to Enrique Font, from the Instituto Cavanilles de Biodiver­sidad y Biologia Evolutiva, and Nader Sanai, MD, at the University of California San Francisco, for their comments and suggestions on the manuscript. This review was supported by CIBERNED and TerCel.

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Authors and Affiliations

  1. Unidad de Neurobiología Comparada, Instituto Cavanilles de Biodiversidad y Biología Evolutiva, Universidad de Valencia, c/ Catedrático José Beltrán nº2, CP 46980, Paterna, Valencia, Spain

    Susana González-Granero, Melissa Lezameta & José Manuel García-Verdugo

  2. Laboratorio de Morfología Celular, Centro de Investigación Príncipe Felipe, Valencia, Spain

    José Manuel García-Verdugo

  3. CIBERNED, Madrid, Spain

    José Manuel García-Verdugo

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  1. Susana González-Granero
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  2. Melissa Lezameta
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  3. José Manuel García-Verdugo
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Correspondence to José Manuel García-Verdugo .

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Editors and Affiliations

  1. Department of Histology and Neuroanatomy, Tokyo Medical University, Tokyo, 160-8402, Japan

    Tatsunori Seki Ph.D. (Professor) (Professor)

  2. Department of Developmental and Regenerative Biology, Institute of Molecular Medicine Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan

    Kazunobu Sawamoto Ph.D. (Professor) (Professor)

  3. Department of Neurology, University of Michigan, 109 Zina Pitcher Place 5021 BSRB, Ann Arbor, MI, 48109, USA

    Jack M. Parent M.D. (Associate Professor) & Arturo Alvarez-Buylla Ph.D. (Professor) (Associate Professor) &  (Professor)

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González-Granero, S., Lezameta, M., García-Verdugo, J.M. (2011). Adult Neurogenesis in Reptiles. In: Seki, T., Sawamoto, K., Parent, J.M., Alvarez-Buylla, A. (eds) Neurogenesis in the Adult Brain I. Springer, Tokyo. https://doi.org/10.1007/978-4-431-53933-9_6

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