Neurogenesis in the Adult Rabbit: From Olfactory System to Cerebellum

  • Giovanna Ponti
  • Federico Luzzati
  • Paolo Peretto
  • Luca Bonfanti


Adult neurogenesis is a feature that is phylogenetically highly conserved, yet most of the current knowledge in this field is based on laboratory rodents. In addition to the differences among vertebrates, remarkable peculiarities are also emerging in the location and structural and functional features of neurogenic ­systems in mammals. Although the orders Lagomorpha and Rodentia are quite similar, unexpected features of structural plasticity and neurogenesis have been found to occur in the rabbit central nervous system. The structural and temporal characteristics of protracted and persistent neurogenesis in rabbits are herewith addressed. Attention is focused on the subventricular zone cytoarchitecture and extensions, as well as on processes of persistent neurogenesis that have been recently demonstrated to occur in the striatum and in the cerebellum. The existence of neural cell progenitors persisting within the rabbit brain parenchyma (so-called nonneurogenic in rodents) are discussed.


Olfactory Bulb Cerebellar Cortex Stem Cell Niche Neuronal Progenitor Rostral Migratory Stream 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



This work was supported by Compagnia di San Paolo (Progetto NEUROTRANSPLANT-2004.2019).


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Copyright information

© Springer 2011

Authors and Affiliations

  • Giovanna Ponti
    • 1
    • 4
  • Federico Luzzati
    • 2
    • 4
  • Paolo Peretto
    • 2
    • 3
    • 4
  • Luca Bonfanti
    • 1
    • 3
    • 4
  1. 1.Department of Veterinary MorphophysiologyUniversity of TurinTurinItaly
  2. 2.Department of Animal and Human BiologyUniversity of TurinTurinItaly
  3. 3.National Institute of Neuroscience-Italy (INN)TurinItaly
  4. 4.Istituto scientifico Fondazione Cavalieri OttolenghiTurinItaly

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