Health Monitoring

  • Shiho Fujita
Part of the Primatology Monographs book series


The great apes face many threats to their continued existence in the wild, and one of these threats is disease. Especially in the populations that are habituated for tourism or research purposes, the great apes are faced with a high risk of disease transmission from humans. Periodic monitoring of their health status is therefore necessary. Noninvasive samples such as urine and feces can be repeatedly obtained from habituated animals without necessitating their capture. Based on the analysis of noninvasive samples, I provide here some preliminary data on health monitoring among the chimpanzees of Bossou, southeastern Guinea, West Africa.


Health Monitoring Intestinal Microflora Negative Energy Balance Juvenile Male Urinary Glucose 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



I sincerely thank the Direction Nationale de la Recherche Scientifique et Technologique (DNRST), and the Institut de Recherche Environnementale de Bossou (IREB) of the Republic of Guinea, for permission to study the chimpanzees at Bossou; and the Tanzania Commission for Science and Technology (COSTECH), the Tanzania Wildlife Research Institute (TAWIRI), the Tanzania National Parks (TANAPA), the Mahale Wildlife Research Centre (MWRC), and the Mahale Mountains National Park (MMNP) for permission to study the chimpanzees at Mahale. This study was financed by a grant from the Research Fellowships of the Japan Society for the Promotion of Science for Young Scientists (No. 4502, 2628), and the Ministry of Education, Culture, Sports, Science and Technology, Japan (No. 12375003).


  1. Allen SD, Emery CL, Lyerly DM (2003) Clostridium. In: Murray PR, Baron EJ, Jorgensen JH, Pfaller MA, Yolken RH (eds) Manual of clinical microbiology, 8th edn, vol 1. ASM Press, Washington, pp 835–856Google Scholar
  2. Bermejo M, Rodriguez-Teijeiro JD, Illera G, Barroso A, Vila C, Walsh PD (2006) Ebola outbreak killed 5000 gorillas. Science 314:1564–1564PubMedCrossRefGoogle Scholar
  3. Boesch C, Boesch-Achermann H (2000) The chimpanzees of the Taï forest. Oxford University Press, OxfordGoogle Scholar
  4. Borriello SP (1995) Clostridial disease of the gut. Clin Infect Dis 20(Suppl 2):S242–S250PubMedCrossRefGoogle Scholar
  5. Chapman CA, Gillespie TR, Goldberg TL (2005) Primates and the ecology of their infectious diseases: how will anthropogenic change affect host-parasite interactions? Evol Anthropol 14:134–144CrossRefGoogle Scholar
  6. Ferber D (2000) Human diseases threaten great apes. Science 289:1277–1278PubMedCrossRefGoogle Scholar
  7. Formentry P, Boesch C, Wyers M, Steiner C, Donati F, Dind F, Walker F, Le Guenno B (1999) Ebola virus outbreak among wild chimpanzees living in a rain forest of Côte d’Ivoire. J Infect Dis 179 (Suppl. 1):S120–S126CrossRefGoogle Scholar
  8. Fujita S, Kageyama, T (2007) Polymerase chain reaction detection of Clostridium perfringens in feces from captive and wild chimpanzees, Pan troglodytes. J Med Primatol 36:25–32PubMedCrossRefGoogle Scholar
  9. Goodall J (1986) The chimpanzees of Gombe: patterns of behavior. Belknap Press of Harvard University Press, CambridgeGoogle Scholar
  10. Hanamura S, Kiyono M, Nakamura M, Sakamaki T, Itoh N, Zamma K, Kitopeni R, Matumula M, Nishida T (2006) A new code of observation employed at Mahale prevention against a flu-like disease. Pan Africa News 13:13–16Google Scholar
  11. Hatheway CL (1990) Toxigenic Clostridia. Clin Microbiol Rev 3:66–98PubMedGoogle Scholar
  12. Hoasaka K (1995) Mahale: a single flu epidemic killed at least 11 chimps. Pan Africa News 2:3–4Google Scholar
  13. Homsy J (1999) Ape tourism and human diseases: how close should we get? Report to the International Gorilla Conservation Programme. <>
  14. Kalema-Zikusoka G, Kock RA, Macfie EJ (2002) Scabies in free-ranging mountain gorillas (Gorilla beringei beringei) in Bwindi Impenetrable National Park, Uganda. Vet Rec 150:12–15PubMedCrossRefGoogle Scholar
  15. Kaur T, Huffman MA (2004) Descriptive urological record of chimpanzees (Pan troglodytes) in the wild and limitations associated with using multi-reagent dipstick test strips. J Med Primatol 33:187–196PubMedCrossRefGoogle Scholar
  16. Knott CD (1996) Monitoring health status of wild orangutans through field analysis of urine. Am J Physiol Anthropol (Suppl) 22:139–140Google Scholar
  17. Knott CD (1998) Changes in orangutan caloric intake, energy balance, and ketones in response to fluctuating fruit availability. Int J Primatol 19:1061–1079CrossRefGoogle Scholar
  18. Köndgen S, Kühl H, N’Goran PK, Walsh PD, Schenk S, Ernst N, Biek R, Formenty P, Mätz-Rensing K, Schweiger B, Junglen S, Ellerbrok H, Nitsche A, Briese T, Lipkin WI, Pauli G, Boesch C, Leendertz FH (2008) Pandemic human viruses cause decline of endangered great apes. Curr Biol 18:260–264PubMedCrossRefGoogle Scholar
  19. Krief S, Huffman MA, Sévenet T, Guillot J, Bories C, Hladik CM, Wrangham RW (2005) Noninvasive monitoring of the health of Pan troglodytes schweinfurthii in the Kibake National Park, Uganda. Int J Primatol 26:467–490CrossRefGoogle Scholar
  20. Leendertz FH, Ellerbrok H, Boesch C, Couacy-Hymann E, Matz-Rensing K, Hakenbeck R, Bergmann C, Abaza P, Junglen S, Moebius Y, Vigilant L, Formenty P, Pauli G (2004) Anthrax kills wild chimpanzees in a tropical rainforest. Nature 430:451–452PubMedCrossRefGoogle Scholar
  21. Leendertz FH, Pauli G, Maetz-Rensing K, Boardman W, Nunn C, Ellerbrok H, Jensen SA, Junglen S (2006b) Pathogens as drivers of population declines: the importance of systematic monitoring in great apes and other threatened mammals. Biol Conserv 131:325–337CrossRefGoogle Scholar
  22. Leory EM, Rouquet P, Formentry P, Souquière S, Kibourne A, Froment J-M, Bermejo M, Smit S, Karesh W, Swanepoel R, Zaki SR, Rollin PE (2004) Multiple ebola virus transmission events and rapid decline of central African wildlife. Science 303:387–390CrossRefGoogle Scholar
  23. Lonsdorf EV, Travis D, Pusey AE, Goodall J (2006) Using retrospective health data from the Gombe chimpanzee study to inform future monitoring efforts. Am J Primatol 68:897–908PubMedCrossRefGoogle Scholar
  24. Matsuzawa T (1992) Death of a chimpanzee and care of the dead infant. Hattatsu 50:95–104 (in Japanese)Google Scholar
  25. Matsuzawa T, Humle T, Koops K, Biro D, Hayashi M, Sousa C, Mizuno Y, Kato A, Yamakoshi G, Ohashi G, Sugiyama Y, Kourouma M (2004) Wild chimpanzees at Bossou-Nimba: deaths through a flu-like epidemic in 2003 and the green-corridor project. Primate Res 20:45–55 (in Japanese)CrossRefGoogle Scholar
  26. McDonel JL (1980) Clostridium perfringens toxins (type A, B, C, D, E). Pharmacol Ther 10:617–655PubMedCrossRefGoogle Scholar
  27. Mitsuoka T (1982) Recent trends in research on intestinal flora. Bifidobacteria Microflora 1:3–24Google Scholar
  28. Niilo L (1980) Clostridium perfringens in animal diseases: a review of current knowledge. Can Vet J 21:141–148PubMedGoogle Scholar
  29. Nishida T, Corp N, Hamai M, Hasegawa T, Hiraiwa-Hasegawa M, Hosaka K, Hunt KV, Itoh N, Kawanaka K, Matsumono-Oda A, Mitani JC, Nakamura M, Norikoshi K, Sakamaki T, Turner L, Uehara S, Zamma K (2003) Demography, female life history, and reproductive profiles among the chimpanzees of Mahale. Am J Primatol 59:99–121PubMedCrossRefGoogle Scholar
  30. Rouquet P, Friment J-M, Bermejo M, Kibourn A, Karesh W, Reed P, Kumulungui B, Yaba P, Délicat A, Rollin PE, Leroy EM (2005) Wild animal mortality monitoring and human ebola outbreaks, Gabon and Republic of Congo, 2001-2003. Emerg Infect Dis 11:283–290PubMedCrossRefGoogle Scholar
  31. Saito M (1990) Production of enterotoxin by Clostridium perfringens derived from human, animals, foods, and the natural environment in Japan. J Food Prot 53:115–118Google Scholar
  32. Smedley JG III, Fisher DJ, Sayeed S, Chakrabarti G, McClane BA (2004) The enteric toxins of Clostridium perfringens. Rev Physiol Biochem Pharmacol 152:183–204PubMedCrossRefGoogle Scholar
  33. Songer JG (1996) Clostridial enteric diseases of domestic animals. Clin Microbiol Rev 9:216–234PubMedGoogle Scholar
  34. Wallis J, Lee DR (1999) Primate conservation: the prevention of disease transmission. Int J Primatol 20:803–826CrossRefGoogle Scholar

Copyright information

© Springer 2011

Authors and Affiliations

  1. 1.Department of Veterinary Medicine, Faculty of AgricultureYamaguchi UniversityYamaguchiJapan

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