Modeling Cellular Dynamics

Part of the A First Course in “In Silico Medicine” book series (FCISM, volume 1)


Cells are the basic units of biological structure and functions. They make up tissues and our bodies. A single cell includes organelles and intracellular solutions, and it is separated from outer environment of extracellular liquid surrounding the cell by its cell membrane (plasma membrane), generating differences in concentrations of ions and molecules including enzymes. The differences in charges of ions and concentrations cause, respectively, electrical and chemical potentials, generating transportations of materials across the membrane. Here we look at cores of mathematical modeling associated with dynamic behaviors of single cells as well as bases of numerical simulations.


Sarcoplasmic Reticulum Port Input Activation Gate Nernst Potential Membrane Potential Versus 

Copyright information

© Springer 2011

Authors and Affiliations

  1. 1.Mechanical Science and Bioengineering Graduate School of Engineering ScienceOsaka UniversityToyonakaJapan
  2. 2.The Center for Advanced Medical Engineering and InformaticsOsaka UniversityToyonakaJapan

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