Vanishing leukoencephalopathy is a vacuolating leukoencephalopathy with subcortical cysts. Symptoms develop at 18 months to 5 years of age with slowly progressive cerebellar ataxia, spasticity, variable optic atrophy, late development of bulbar symptoms, and preserved mental capacities. There are adult cases.


White Matter Metachromatic Leukodystrophy Infantile Form Hirano Body Bulbar Symptom 
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18 Leukodystrophy

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