Abstract
Wernicke’s encephalopathy is a serious neurological disorder caused by vitamin B1 or thiamine deficiency, chiefly in chronic alcoholics and rarely in children. It may be associated with starvation, prolonged intravenous treatment without vitamin supplementation, hemodialysis, and gastric stapling. The classic triad of clinical symptoms described by Wernicke (gait ataxia, ophthalmoplegia, confusion) are found in only one-third of patients during the initial examination.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
14 Mitochondrial Cytopathy
Harper C, Butterworth R (2002) Nutritional and metabolic disorders. In: Graham DI, Lantos PL (eds) Greenfields’ neuropathology, 7th edn, Vol 1. Arnold, London, pp 610–618.
Makino M, Horai S, Goto Y, Nonaka I (2000) Mitochondrial DNA mutations in Leigh syndrome and their phylogenetic implications. J Hum Genet 45:69–75.
Prasson RA, Whang N (2002) Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome: an autopsy report. Arch Pathol Lab Med 122:978–981.
Powers JM, DeVivo DC (2002) Peroxisomal and mitochondrial disorders. In: Graham DI, Lantos PL (eds) Greenfields’ neuropathology, 7th edn, Vol 1. Arnold, London, pp 485–488, 780–784.
Ohama E, Ohara S, Ikuta F, Ikuta F, Tanaka K, Nishizawa M, Miyatake T (1987) Mitochondrial angiopathy in cerebral blood vessels of mitochondrial encephalomyopathy Acta Neuropathol (Berl) 74:226–233.
Chow CW, Thorburn DR (2000) Morphological correlates of mitochondrial dysfunction in children. Hum Reprod 15(Suppl 2):68–78.
Rights and permissions
Copyright information
© 2007 Springer
About this chapter
Cite this chapter
(2007). Mitochondrial Cytopathy. In: Pediatric Neuropathology. Springer, Tokyo. https://doi.org/10.1007/978-4-431-49898-8_14
Download citation
DOI: https://doi.org/10.1007/978-4-431-49898-8_14
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-70246-7
Online ISBN: 978-4-431-49898-8
eBook Packages: MedicineMedicine (R0)