The cerebral surface develops gradually from the fetal flat (lissencephalic) brain to the adult gyral pattern, increasing the cortical surface area until the second year of life. The sylvian fissure is apparent at approximately 14 weeks’ gestation (GW). The primary sulci, such as rolandic, calcarine, superior temporal, and precentral sulci, appear after 20 GW, the secondary sulci appear from 28 GW, and the tertiary sulci from 36 GW. The gestational age of a brain can be estimated by counting the number of convolutions (gyri) crossed by a line drawn from the frontal to the occipital pole above the insula and adding 21 to the gyral count . Gestational age can also be estimated by counting gyri and sulci in neuroimages [ultrasonography and magnetic resonance imaging (MRI)].
KeywordsFetal Brain Cerebral White Matter Deep White Matter Basal Dendrite Germinal Matrix
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1 Normal Development
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