Glucose Dilution in Practice

Abstract

In the previous chapters, we used the term glucose space for the distribution volume of glucose. From this chapter on, we advocate initial distribution volume of glucose (IDVG) instead, because our glucose space does not cover the entire glucose distribution but rather its initial distribution phase only. Original measurement of our IDVG requires repeated blood sampling throughout 7 min postinjection and applying a one-compartment model to the incremental values above preinjection. In this chapter, the measurement procedure of original IDVG, its normal value, its repeatability, and its approximation are described.