Abstract
In this article, we will discuss how the Wisdom Web (WW) from the next-generation Web Intelligence (WI) development contributes to the research studies in immunology, i.e., the scientific discovery of HIV-immune interaction dynamics. In particular, we will show that a new computing paradigm, called Autonomy Oriented Computing (AOC), will be necessary to support the Wisdom Web to meet this challenge. Throughout our discussion, we will pose several Research Questions, through which the authors intend to highlight the technical issues involved and to stimulate thinking and innovations from the community of researchers pursuing this exciting, interdisciplinary endeavor.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Coffin J M (1995) HIV population dynamics in Vivo: Implications for genetic variation, pathogenesis, and therapy. Science 267:483–489
Fauci A S (1988) The immunodeficiency virus: Infectivity and mechanisms of pathogenesis. Science 239:617–622
Hershberg U, Louzoun Y, Atlan H, Solomon S (2000) HIV time hierarchy: Winning the war while loosing all the battles. Physica A 289:178–190
Jin X, Liu J (2004) From individual based modeling to autonomy oriented computation. In: Nickles M, Rovatsos M, Weiss, G. (eds) Agents and Computational Autonomy, LNAI 2969. Springer, pp. 151–169
Kauffman S (1993) Origins of Order: Self-Organization and Selection in Evolution. Oxford University Press
Liu J (2003) Web Intelligence (WI): What makes Wisdom Web? Proceedings of the Eighteenth International Joint Conference on Artificial Intelligence (IJCAI-03), Acapulco, Mexico, Aug. 9–15, 2003. Morgan Kaufmann Publishers, pp. 1596–1601 (invited talk)
Liu J (2001) Autonomous Agents and Multi-Agent Systems: Explorations in Learning, Self-Organization and Adaptive Computation. World Scientific.
Liu J, Han J, Tang Y Y (2002) Multi-agent oriented constraint satisfaction. Artificial Intelligence 136(1): 101–144
Liu J, Jin X, Tang Y (2004) Multi-agent collaborative service and distributed problem solving. Cognitive Systems Research 5(3):191–206
Liu J, Jin X, Tsui K C (2005a) Autonomy Oriented Computing (AOC): From Problem Solving to Complex Systems Modeling. Springer/Kluwer Academic Publishers
Liu J, Jin X, Tsui K C (2005b) Autonomy Oriented Computing (AOC): Formulating computational systems with autonomous components. IEEE Trans actions on Systems, Man and Cybernetics, Part A: Systems and Humans 35(6):879–902
Liu J, Jin X, Wang S (2005c) Agent-based load balancing on homogeneous minigrids: Macroscopic modeling and characterization. IEEE Transactions on Parallel and Distributed Systems 16(7):586–598
Liu J, Zhong N, Yao Y Y, Ras Z W (2003) The Wisdom Web: New challenges for Web Intelligence (WI). Journal of Intelligent Information Systems 20(1)
McCune J M (2001) The dynamics of CD4+ T-cell depletion in HIV disease. Nature 410:974–979
Perelson A S, Newmann A U, Markowitz M, Leonard J M, Ho D D (1996) HIV-1 dynamics in Vivo: Virion clearance rate, infected cell life-span, and viral generation time. Science 271:1582–1586
Wei X, et al. (1995) Viral dynamics in Human Immunodeficiency Virus Type 1 Infection. Nature 373:117–122
Yao Y Y, Zhong N, Liu J, Ohsuga S (2001) Web Intelligence (WI): Research challenges and trends in the new information age. Web Intelligence: Re search and Development, LNAI 2198. Springer, pp. 1–17
Zhang S, Liu J (2005) A massively multi-agent system for discovering HIV-immune interaction dynamics. In: Ishida T, Gasser L, Nakashima H (eds) Massively Multi-Agent Systems, LNCS. Springer, pp. 161–173
Zhong N, Liu J, Yao Y Y (2002) In search of the Wisdom Web. IEEE Computer 35:27–31
Zhong N, Liu J, Yao Y Y (2003) (eds) Web Intelligence. Springer
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2007 Springer
About this chapter
Cite this chapter
Liu, J., Zhong, N., Yao, Y., Wu, JL. (2007). Web Intelligence Meets Immunology. In: Wu, J.L., Ito, K., Tobimatsu, S., Nishida, T., Fukuyama, H. (eds) Complex Medical Engineering. Springer, Tokyo. https://doi.org/10.1007/978-4-431-30962-8_19
Download citation
DOI: https://doi.org/10.1007/978-4-431-30962-8_19
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-30961-1
Online ISBN: 978-4-431-30962-8
eBook Packages: EngineeringEngineering (R0)