Skip to main content
SpringerLink
Log in

Sound Localization and Lateralization of Patients with Auditory Neuropathy

  • Conference paper
Neuropathies of the Auditory and Vestibular Eighth Cranial Nerves

  • 1003 Accesses

Abstract

To investigate the spatial abilities of patients with auditory neuropathy (auditory nerve disease, AN), we applied a sound localization task with a speaker array as well as a binaural sound lateralization task. In the sound localization task, subjects were asked to choose the direction of actual sound source of short (duration, 3 ms) or long (duration, 100 ms) noise bursts centered at 500 Hz played from 1 of 12 surrounding (220°) speakers. The AN patients identifi ed the direction of the longduration sound fairly well. However, they could localize few sources of the shortduration sound. The results were compared with non-AN patients and normal persons to discuss the auditory neural processing of cues for transient or prolonged source estimation, that is, interaural intensity and time differences (IID, ITD) and spectral difference by head-related transfer function (HRTF).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Butler RA, Humanski RA, Musicant AD (1990) Binaural and monaural localization of sound in two-dimensional space. Perception 19:241–256

    Article  PubMed  CAS  Google Scholar 

  2. Palomäki KJ, Tiitinen H, Mäkinen V, May PJ, Alku P (2005) Spatial processing in human auditory cortex: the effects of 3D, ITD, and ILD stimulation techniques. Cogn Brain Res 24:7640–7647

    Article  Google Scholar 

  3. Kaga K, Nakamura M, Shinogami M, et al (1996) Auditory nerve disease of both ears revealed by auditory brainstem responses, electrocochleography and otoacoustic emissions. Scand Audiol 25:233–238

    PubMed  CAS  Google Scholar 

  4. Starr A, Picton TW, Sininger Y, et al (1996) Auditory neuropathy. Brain 119:741–753

    Article  PubMed  Google Scholar 

  5. Kulkarni A, Colburn HS (1998) Role of spectral detail in sound-source. Nature (Lond) 396:747–749

    Article  CAS  Google Scholar 

  6. Shackleton TM, Bowsher JM, Meddis R (1991) Lateralization of very-short-duration tone pulses of low and high frequencies. Q J Exp Psychol A 43:503–516

    PubMed  CAS  Google Scholar 

  7. Itoh K (1985) A neuro-synaptic model of auditory-masking and unmasking process. Biol Cybern 52:229–235

    Article  PubMed  CAS  Google Scholar 

  8. Joris P, Yin TC (2007) A matter of time: internal delays in binaural processing. Trends Neurosci 30:70–78

    Article  PubMed  CAS  Google Scholar 

  9. Darrow KN, Maison SF, Liberman MC (2006) Cochlear efferent feedback balances interaural sensitivity. Nat Neurosci 9:1474–1476

    Article  PubMed  CAS  Google Scholar 

  10. Shepherd RK, Roberts LA, Paolini AG (2004) Long-term sensorineural hearing loss induces functional changes in the rat auditory nerve. Eur J Neurosci 20:3131–3140

    Article  PubMed  Google Scholar 

  11. van Hoesel R, Böhm M, Pesch J, et al (2008) Binaural speech unmasking and localization in noise with bilateral cochlear implants using envelope and fi ne-timing based strategies. J Acoust Soc Am 123:2249–2263

    Article  PubMed  Google Scholar 

  12. Narne VK, Vanaja CS (2008) Speech identifi cation and cortical potentials individuals with auditory neuropathy. Behav Brain Funct 4:15

    Article  PubMed  Google Scholar 

  13. Moore BC (2002) Interference effects and phase sensitivity in hearing. Philos Transact A Math Phys Eng Sci 360:833–858

    Article  PubMed  Google Scholar 

  14. Dreyer A, Delgutte B (2006) Phase locking of auditory-nerve fi bers to the envelopes of high-frequency sounds: implications for sound localization. J Neurophysiol 96:2327–2341

    Article  PubMed  Google Scholar 

  15. Santarelli R, Starr A, Michalewski HJ, et al (2008) Neural and receptor cochlear potentials obtained by transtympanic electrocochleography auditory neuropathy. Clin Neurophysiol 119:653–661

    Article  Google Scholar 

  16. Moser T, Neef A, Khimich D (2006) Mechanisms underlying the temporal precision of sound coding at the inner hair cell ribbon synapse. J Physiol 576:55–62

    Article  PubMed  CAS  Google Scholar 

  17. Roux I, Safieddine S, Nouvian R, et al (2006) Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse. Cell 127:277–289

    Article  PubMed  CAS  Google Scholar 

  18. Heil P, Neubauer H, Irvine DR, et al (2007) Spontaneous activity of auditory-nerve fibers: insights into stochastic processes at ribbon synapses. J Neurosci 27:8457–8474

    Article  PubMed  CAS  Google Scholar 

  19. Ceranic B, Luxon LM (2004) Progressive auditory neuropathy in patients with Leber’s hereditary optic neuropathy. J Neurol Neurosurg Psychiatry 75:626–630

    Article  PubMed  CAS  Google Scholar 

  20. Aytekin M, Moss CF, Simon JZ (2008) A sensorimotor approach to sound localization. Neural Comput 20:603–635

    Article  PubMed  Google Scholar 

  21. Niu X, Tahera Y, Canlon B (2007) Environmental enrichment to sound activates dopaminergic pathways in the auditory system. Physiol Behav 92:34–39

    Article  PubMed  CAS  Google Scholar 

  22. Kral A, Eggermont JJ (2007) What’s to lose and what’s to learn: development under auditory deprivation, cochlear implants and limits of cortical plasticity. Brain Res Rev 56:259–269

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Sensory and Motor Neuroscience, The University of Tokyo School of Medicine, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan

    Kenji Itoh, Sozo Kuroki & Sotaro Sekimoto

  2. National Institute of Sensory Organs, National Tokyo Medical Center, 2-5-1 Higashigaoka, Megur-ku, Tokyo, 152-8902, Japan

    Kimitaka Kaga

Authors
  1. Kenji Itoh
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Sozo Kuroki
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Sotaro Sekimoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Kimitaka Kaga
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. The University of Tokyo, Tokyo, Japan

    Kimitaka Kaga M.D., Ph.D. (Emeritus Professor, Director) (Emeritus Professor, Director)

  2. National Institute of Sensory Organs, National Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo, 152-8902, Japan

    Kimitaka Kaga M.D., Ph.D. (Emeritus Professor, Director) (Emeritus Professor, Director)

  3. Department of Neurology and Neurobiology, University of California Irvine, Irvine, CA, 92717, USA

    Arnold Starr M.D. (Professor) (Professor)

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Springer

About this paper

Cite this paper

Itoh, K., Kuroki, S., Sekimoto, S., Kaga, K. (2009). Sound Localization and Lateralization of Patients with Auditory Neuropathy. In: Kaga, K., Starr, A. (eds) Neuropathies of the Auditory and Vestibular Eighth Cranial Nerves. Springer, Tokyo. https://doi.org/10.1007/978-4-431-09433-3_4

Download citation

  • DOI: https://doi.org/10.1007/978-4-431-09433-3_4

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-09432-6

  • Online ISBN: 978-4-431-09433-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation