Skip to main content
SpringerLink
Log in

Molekulare Immunologie

  • Chapter
Immunologie für Einsteiger

  • 9725 Accesses

Zusammenfassung

In diesem Kapitel wollen wir die molekularen Grundlagen der Signalweiterleitung in Leukocyten und die genetische Grundlage der Vielfalt von Antikörpern und T-Zell-Rezeptoren besprechen.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 44.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Gellert, M (2002) V(D)J Recombination: RAG Proteins, Repair Factors, and Regulation. Annu Rev Biochem 71: 191–132

    Article  Google Scholar 

  • Haase H, Rink L (2009) Functional significance of zincrelated signaling pathways in immune cells. Annu Rev Nutr 29: 133–152

    Article  PubMed  CAS  Google Scholar 

  • Hoffbrand AV, Catovsky D, Tuddenham EGD (Hrsg.) (2005) Postgraduate Haematology. 5th Edition Blackwell Publishing Ltd., Hoboken, NJ

    Google Scholar 

  • Hozumi N, Tonegawa S (1976) Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions. Proc Natl Acad Sci USA 73(10): 3628–3632

    Article  PubMed  CAS  Google Scholar 

  • Köhler G, Milstein C (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256: 495–497

    Article  PubMed  Google Scholar 

  • Krauss G (2008) Biochemistry of Signal Transduction and Regulation, 4. Aufl. Wiley-VCH, Weinheim

    Google Scholar 

  • O’Connell RM, Rao DS, Chaudhuri AA, Baltimore D (2010) Physiological and pathological roles for microRNAs in the immune system. Nat Rev Immunol 10(2): 111–122

    Article  CAS  Google Scholar 

  • Peled JU, et al. (2008) The Biochemistry of Somatic Hypermutation. Annu Rev Immunol 26: 481–511

    Article  PubMed  CAS  Google Scholar 

  • Stavenezer J, Guikema JEJ, Schrader CE (2008) Mechanism and Regulation of Class Switch Recombination. Annu Rev Immunol 26: 261–292

    Article  Google Scholar 

  • Steinitz M (2009) Three decades of human monoclonal antibodies: Past, present and future developments. Human Antibodies 18: 1–10

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institut für Immunologie, Universitätsklinikum Aachen, Deutschland

    Prof. Dr. rer. nat. Lothar Rink & Dr. rer. nat. Hajo Haase

  2. Institut für Systemische Entzündungsforschung, Universitätsklinikum Schleswig-Holstein, Deutschland

    PD Dr. rer. nat. Andrea Kruse

Authors
  1. Prof. Dr. rer. nat. Lothar Rink
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. PD Dr. rer. nat. Andrea Kruse
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Dr. rer. nat. Hajo Haase
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Spektrum Akademischer Verlag Heidelberg

About this chapter

Cite this chapter

Rink, L., Kruse, A., Haase, H. (2012). Molekulare Immunologie. In: Immunologie für Einsteiger. Spektrum Akademischer Verlag, Heidelberg. https://doi.org/10.1007/978-3-8274-2440-2_6

Download citation

Publish with us

Policies and ethics

Search

Navigation