Advertisement

The Crosslinked Ultra-high Molecular Weight Polyethylene: Risk and Limitation

  • L. Costa
  • P. Bracco
  • E. M. del Brach Prever
Conference paper
Part of the Ceramics in Orthopaedics book series (CIO)

Abstract

In the past three decades the majority of the implanted orthopedic prostheses included a bearing component made of ultrahigh molecular weight polyethylene (UHMWPE) articulating against a femoral metallic or ceramic ball or a metallic tibial plateau. Wear of the polyethylene bearing surfaces produces abrasion particles [1], often causing a foreign body response that may lead to bone resorption (osteolysis) and loosening of the components, and thereby limiting the life expectancy of hip prostheses. Thus, improving the wear resistance of the polyethylene can substantially extend the clinical life span of total hip prostheses.

Keywords

Wear Resistance Ethylene Oxide Bond Scission Ceramic Ball Foreign Body Response 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    McKellop, H.A.; Campbell, P., Park, S.H.; Schmalzried, T.P.; Grigoris, P.; Amstutz, H.C.; Sarmiento A: The origin of submicron polyethylene wear debris in total hip arthroplasty. Clin Orthop 311:3–20, 1995PubMedGoogle Scholar
  2. 2.
    Costa, L; Luda, M.P.; Trossarelli, L; Brach del Prever, E.M.; Crova, M.; Gallinaro, P.: Oxidation in orthopaedic UHMWPE sterilized by gamma-radiation and ethylene oxide. Biomaterials, 19:659–1998.Google Scholar
  3. 3.
    Kurtz, S.M., Muratoglu, O.K.; Evans, M.; Edidin, A.A.: Advances in the processing, sterilization, and crosslinking of UHMWPE for total joint arthroplasty. Biomaterials, 20:1659–1688, 1999.PubMedCrossRefGoogle Scholar
  4. 4.
    McKellop, H.; Shen, F.-W.; Lu., B.; Salovey, R.; Campbell, P.: The effect of sterilization method and other modifications on the wear resistance of acetabular cups of ultra-high molecular weight polyethylene. A hip simulator study. J. Bone and Joint Surgery, 82-A(12), 1708–1725, 2000Google Scholar
  5. 5.
    Fisher, J,; Reeves, E. A.; Isaac, G. H.; Saum, K. A.; and Sanford, W. M.: Comparison of the wear of aged and non-aged UHMWPE sterilized by gamma irradiation and by gas plasma. J. Mater. Sci. Mater. Med., 8:375–378, 1997.PubMedCrossRefGoogle Scholar
  6. 6.
    Costa L. and Brach del Prever E.M. “UHMWPE for Arthroplasty” Edizione Minerva Medica Torino 2000.Google Scholar
  7. 7.
    Shen, F.-W.; McKellop, H.: Interaction of oxidation and crosslinking in gamma-irradiated ultra-high molecular weight polyethylene. J Biomedical Materials Research, 61:430–439, 2002.CrossRefGoogle Scholar
  8. 8.
    McKellop, H.; Shen, F.-W.; Lu, B.; Campbell, P.; Salovey, R.: Development of an extremely wear resistant UHMW polyethylene for total hip replacements. J. Orthopaedic Research. 17(2), 157–167, 1999CrossRefGoogle Scholar
  9. 9.
    Muratoglu, O.K.; Bragdon, C.R.; O’Connor, D.O.; Jasty, M.; Harris, W.H.: A novel method of crosslinking UHMWPE to improve wear, reduce oxidation, and retain mechanical properties. J Arthroplasty, 16:149–160, 2001.PubMedCrossRefGoogle Scholar
  10. 10.
    Saikko, V.; Calonius, O.; Keranen, J.: Wear of conventional and crosslinked UHMWPE acetabular cups against polished and roughened CoCr femoral heads in biaxial hip simulator. J Biomed Mater Res (Appl Biomater), 63:848–853, 2002.CrossRefGoogle Scholar
  11. 11.
    Affatato, S.; Bordini, B.; Fagnano, C; Taddei, P.; Tinti, A.; Toni, A.: Effects of the sterilization method on the wear of UHMWPE acetabular cups tested in a hip joint simulator. Biomaterials, 23:1439–1446, 2002.PubMedCrossRefGoogle Scholar
  12. 12.
    Grobbelaar, C. J.; Plessis, T. A. D.; Marais, F.: The radiation improvement of polyethylene prostheses. J. Bone and Joint Surg., 60-B:370–374, 1978.Google Scholar
  13. 13.
    Grobbelaar, C.J.; Weber, F.A.; Spirakis, A.; et al.: Clinical experience with gamma irradiation-crosslinked polyethylene — A 14 to 20 year follow-up report. South African Bone and Joint Surgery, XI(3):140–147, 1999.Google Scholar
  14. 14.
    Oonishi, H.; Takayama, Y.; and Tsuji, E.: Improvement of polyethylene by irradiation in artificial joints. Radiat. Phys. Chem., 39:495–504, 1992.Google Scholar
  15. 15.
    Oonishi, H.; Saito, M.; Kadoya, Y.: Wear of high-dose gamma irradiated polyethylene in total hip replacement: Long term radiological evaluation. Trans Orthop Res Soc, p97, 1998.Google Scholar
  16. 16.
    Wroblewski, B.M.; Siney, P.D.; Fleming, P.A.: Low-friction arthroplastyof the hip using alumina ceramic and crosslinked polyethylene: A ten-year follow-up report. J Bone Joint Surg., 81-B:54–55, 1999.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • L. Costa
  • P. Bracco
  • E. M. del Brach Prever

There are no affiliations available

Personalised recommendations