• Dietrich Abeck
  • Walter Burgdorf
  • Hansjoerg Cremer


Vehicles for topical agents is an issue which rarely concerns physicians other than dermatologist. The vehicle is the cream, ointment or liquid in which an active ingredient is mixed. There is an old saying to the effect that a skilled dermatologist can achieve more by employing the ideal vehicle for a given disease at a certain stage than can an inexperienced physician with the entire spectrum of active ingredients, but no concept of when to use what. It is absolutely crucial to understand the different types of vehicles in which topical medications can be mixed and to employ them with fine touch. In many instances, the drying, lubricating or soothing action of the vehicle plays as great a role as the choice of active ingredients. Conversely, applying exactly the wrong vehicle can countermand even the most appropriately chosen active ingredient. Table 65 lists common vehicles, while Table 66 correlates clinical findings with appropriate and less appropriate vehicles.


Atopic Dermatitis Active Ingredient Allergic Rhinitis Topical Corticosteroid Triamcinolone Acetonide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Abeck D., Cremer H., Pflugshaupt C., Ring J.: Stadienorientierte Auswahl dermatologischer Grundlagen („Vehikel“) bei der örtlichen Therapie des atopischen Ekzems. pädiatrische praxis 52:113–121 (1997)Google Scholar
  2. Pharmazeutisches Laboratorium des „Neues Rezeptur-Formularium“Google Scholar
  3. Standardisierte Rezepturen (NRF/SR) 2001. Govi, Eschborn (2001)Google Scholar
  4. Weston W.L., Lane A.T., Morelli J.G.: Dermatopharmacology and Topical Formulary pp. 322–331. 3rd edition. Mosby, St. Louis (2002)Google Scholar


  1. Abeck D., Korting H.C., Mempel M.: Pyodermien. Hautarzt 49:243–252 (1998)PubMedCrossRefGoogle Scholar
  2. Rote Liste Editio Cantor, Aulendorff (2001)Google Scholar
  3. Epstein M.E., Amodio-Groton M., Sadick N.S.: Antimicrobial agents for the dermatologist. I.-lactam antibiotics and related compounds. Journal of the American Academy of Dermatology 37: 149–165 (1997)PubMedCrossRefGoogle Scholar
  4. Epstein M.E., Amodio-Groton M., Sadick N.S.: Antimicrobial agents for the dermatologist. II. Macrolides, fluoroquinolones, rifamycins, tetracyclines, trimethoprim-sulfamethoxazole, and clindamycin. Journal of the American Academy of Dermatology 37:365–381 (1997)PubMedCrossRefGoogle Scholar
  5. Gloor M., Ringelmann R.: Antibiotika in der Dermatologie. Zeitschrift für Haut-und Geschlecht-skrankheiten 71:672–677 (1996)Google Scholar
  6. Simon C, Stille W.: Antibiotika-Therapie in Klinik und Praxis, 10. Auflage. Schattauer, Stuttgart New York (2000)Google Scholar


  1. Abeck D., Werfel S., Brockow K., Ring J.: Die Behandlung des atopischen Ekzems im Kindesalter. Hautarzt 48:379–383 (1998)CrossRefGoogle Scholar
  2. Diepgen T. L.: Long-term treatment with cetirizine of infants with atopic dermatitis: a multi-country, double-blind, randomized, placebo-controlled trial (the ETAC trade mark trial) over 18 months. Pediatr Allergy Immunol 13:278–286 (2002)PubMedCrossRefGoogle Scholar
  3. Reider N., Zloczower M., Fritsch P., Kofler H.: Antihistaminika, Teil; I. Hautarzt 49:674–681 (1998)PubMedCrossRefGoogle Scholar
  4. Reider N., Zloczower M., Fritsch P., Kofler H.: Antihistaminika, Teil II. Hautarzt 49:734–742 (1998)PubMedCrossRefGoogle Scholar
  5. Simons EE.: HI-antihistamines in children. Clin Allergy Immunol 17:437–464 (2002)PubMedGoogle Scholar


  1. Korting H.C.: Dermatotherapie. Springer, Berlin (1995)CrossRefGoogle Scholar
  2. Niedner R. (Hrsg.): Kortikoide in der Dermatologie. UNI-MED, Bremen (1998)Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Dietrich Abeck
    • 1
  • Walter Burgdorf
    • 2
  • Hansjoerg Cremer
    • 3
  1. 1.Klinik und Poliklinik für Dermatologie und Allergologie am BiedersteinTechnische Universität MunchenMunchenGermany
  2. 2.TutzingGermany
  3. 3.HeilbronnGermany

Personalised recommendations