Skip to main content
SpringerLink
Log in

What can psychological treatments say about causes in schizophrenia?

  • Conference paper
Search for the Causes of Schizophrenia

  • 308 Accesses

Abstract

There is increasing interest in the possibility that specific and specifiable psychological treatments can be effective in reducing the symptoms of schizophrenia. What is the evidence for this and what might the amenability of core symptoms to psychological intervention tell us about mechanisms in the pathogenesis and maintenance of psychotic symptoms in schizophrenia?

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Agrawal N, Aleman A, Morgan KD, David AS (2003) Insight in psychosis and neuropsychological function: a meta-analysis. Schizophrenia Research 60(1)(Suppl1): 120

    Article  Google Scholar 

  • Barrowclough C, Haddock G, Tarrier N, Lewis SW, Moring J, O’Brien R, Schofield N, McGovern J (2001) Randomized controlled trial of motivational interviewing, cognitive behavior therapy, and family intervention for patients with comorbid schizophrenia and substance use disorders. Am J Psychiatry 158(10):1706–1713

    Article  PubMed  CAS  Google Scholar 

  • Bilder RM, Volavka J, ál Czobor P, Malhotra AK, Kennedy JL, Ni X, Goldman RS, Hoptman MJ, Sheitman B, Lindenmayer JP, Citrome L, McEvoy JP, Kunz M, Chakos M, Cooper TB, Lieberman JA (2003) Neurocognitive correlates of the COMT Va1158Met polymorphism in chronic schizophrenia. Biological Psychiatry 52(7): 701–707

    Article  Google Scholar 

  • Butzlaff RL, Hooley JM (1998) Expressed emotion and psychiatric relapse: a meta-analysis. Arch Gen Psychiatry 55(6):547–552

    Article  PubMed  CAS  Google Scholar 

  • Drake RJ, Lewis SW (2003) Insight and neurocognition in acute schizophrenia and related disorders. Schizophrenia Research 62(1/2):165–173

    Article  PubMed  Google Scholar 

  • Egan MF, Goldberg TE, Kolachana BS, Callicott JH, Mazzanti CM, Straub RE, Goldman D, Weinberger DR (2001) Effect of COMT Val108/158Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci USA 98(12):6917–6922

    Article  PubMed  CAS  Google Scholar 

  • Frith CD (1992) The cognitive neuropsychology of schizophrenia. LEA press, Hove, UK

    Google Scholar 

  • Garety P, Kuipers E, Fowler D, Freeman D, Bebbington P (2001) A cognitive model of the positive symptoms of psychosis. Psychological Medicine 31:189–195

    Article  PubMed  CAS  Google Scholar 

  • Haddock G, Barrowclough C, Tarrier N, Moring J, O’Brien R, Schofield N, Quinn J, Palmer S, Davies L, Lowens I, McGovern J, Lewis S (2003) Cognitive-behavioural therapy and motivational intervention for schizophrenia and substance misuse. 18-month outcomes of a randomised controlled trial. Br J Psychiatry 183:418–426

    Article  PubMed  Google Scholar 

  • Heaton RK, Chelune GJ, Talley JL, Kay GG, Curtiss G (1993) Wisconsin Card Sorting Test Manual (Psychological Assessment Resources, Odessa, FL)

    Google Scholar 

  • Hemsley DR (1993) A simple (or simplistic?) cognitive model for schizophrenia. Behaviour Research and Therapy 31:633–645

    Article  PubMed  CAS  Google Scholar 

  • Kay SR, Opler LA (1987) The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophrenia Bulletin 13:507–518

    Article  Google Scholar 

  • Kemp R, Hayward P, Applethwaite G, Everritt B, David A (1996) Compliance therapy in psychotic patients: randomised controlled trial. BMJ 312:345–349

    Article  PubMed  CAS  Google Scholar 

  • Kemp R, Kirov G, Everitt B, Hayward P, David A (1998) Randomised controlled trial of compliance therapy: 18-month follow-up. British Journal of Psychiatry 172:413–419

    Article  PubMed  CAS  Google Scholar 

  • Koren D, Seidman LJ, Poyurovski M, Viksman P, Balush V, Goldsmith M, Klein E (2003) Insight in first-episode schizophrenia: a metacognitive neuropsychological study. Schizophrenia Research 60(1)(Suppl 1):173–174

    Article  Google Scholar 

  • Kuipers E, Garety P, Fowler D, Dunn G, Bebbington P, Freeman D, Hadley C (1997) The London-East Anglia randomised controlled trial of cognitive-behavioural therapy for psychosis. I. Effects of the treatment phase. British Journal of Psychiatry 171:319–327

    Article  PubMed  CAS  Google Scholar 

  • Laroi F, Fannemel M, Ronneberg U, Flekkoy K, Opjordsmoen S, Dullerud R, Haakonsen M (2000) Unawareness of illness in chronic schizophrenia and its relationship to structural brain measures and neuropsychological tests. Psychiatry Res 100(1): 49–58

    Article  PubMed  CAS  Google Scholar 

  • Lewis S, Tarrier N, Haddock G, Bentall R, Kinderman P, Kingdon D, Siddle R, Drake R, Everitt J, Leadley K, Benn A, Grazebrook K, Haley C, Akhtar S, Davies L, Palmer S, Faragher B, Dunn G (2002) Randomised controlled trial of cognitive-behavioural therapy in early schizophrenia: acute-phase outcomes. British Journal of Psychiatry 181 (Suppl 43):91–97

    Article  Google Scholar 

  • Linszen DH, Dingemans PM, Lenior ME (1994) Cannabis abuse and the course of re-cent-onset schizophrenic disorders. Archives of General Psychiatry 51(4):273–279

    Article  PubMed  CAS  Google Scholar 

  • Lysaker PH, Bell MD, Bryson G, Kaplan E (1998) Neurocognitive function and insight in schizophrenia: support for an association with impairments in executive function but not with impairments in global function. Acta Psychiatr Scand 97(4):297–301

    Article  PubMed  CAS  Google Scholar 

  • Malhotra AK, Kestler LJ, Mazzanti C, Bates JA, Goldberg T, Goldman D (2002) A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition. Am J Psychiatry 159:652–654

    Article  PubMed  Google Scholar 

  • Mattay VS, Goldberg TE, Fera F, Hariri AR, Tessitore A, Egan MF, Kolachana B, Callicott JH, Weinberger DR (2003) Catechol 0-methyltransferase va1158-met genotype and individual variation in the brain response to amphetamine Proc Natl Acad Sci USA 13; 100(10):6186–6191

    Article  CAS  Google Scholar 

  • McGorry PD, Yung AR, Phillips LJ et al (2002) Randomised controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms. Archives of General Psychiatry 59: 921–928

    Article  Google Scholar 

  • Morrison AP, Bentall RP, French P, Kilcommons A, Walford L, Lewis SW (2002) A randomised controlled trial of early detection and cognitive therapy for preventing transition to psychosis in high risk individuals: study design and interim analysis of transition rate and psychological risk factors. British Journal of Psychiatry 181 (Suppl 43):78–84

    Article  Google Scholar 

  • Mueser KT, Berenbaum H (1990) Psychodynamic treatment of schizophrenia: is there a future? Psychol Med 20:253–262

    Article  PubMed  CAS  Google Scholar 

  • Pharoah FM, Mari JJ, Streiner D (2000) Family intervention for schizophrenia. Cochrane Database Syst Rev (2):CD000088

    PubMed  Google Scholar 

  • Rossell SL, Coakes J, Shapleske J, Woodruff PW, David AS (2003) Insight: its relationship with cognitive function, brain volume and symptoms in schizophrenia. Psychol Med 3(1):111–119

    Google Scholar 

  • Sellwood W, Barrowclough C, Tarrier N, Quinn J, Mainwaring J, Lewis SW (2001) Needs-based cognitive-behavioural family intervention for carers of patients suffering from schizophrenia: 12-month follow-up. Acta Psychiatr Scand 104(5):346–355

    Article  PubMed  CAS  Google Scholar 

  • Sensky T, Turkington T, Kingdon D, Scott JL, Scott J, Siddle R, O’Carroll M, Barnes TRE (2000) A randomised, controlled trial of cognitive behaviour therapy for persistent positive symptoms in schizophrenia resistant to medication. Archives of General Psychiatry 57:165–173

    Article  PubMed  CAS  Google Scholar 

  • Tarrier N, Sharpe L, Beckett R, Harwood S, Baker A, Yusopoff L (1993) A trial of two cognitive behavioural methods of treating drug-resistant residual psychotic symptoms in schizophrenic patients. II. Treatment-specific changes in coping and problem-solving skills. Soc Psychiatry Psychiatr Epidemiol 28(1):5–10

    Article  PubMed  CAS  Google Scholar 

  • Tarrier N, Yusopoff L, Kinney C et al (1998) Randomised controlled trial of intensive cognitive behaviour therapy for patients with chronic schizophrenia. BMJ 317: 303–307

    Article  PubMed  CAS  Google Scholar 

  • Viksman P, Poyurovsky M, Balush V, Levy A, Fuchs E, Eytan Y, Burzstein C, Goldsmith M, Koren D (2002) Metacognition in first episode schizophrenia: its relationship to theory of mind and executive functioning. Schizophrenia Research 53 (3):137

    Google Scholar 

  • Wahlbeck K, Cheine M, Essali MA (2000) Clozapine versus typical neuroleptic medication for schizophrenia. Cochrane Database Syst Rev (2):CD000059

    PubMed  Google Scholar 

  • Weinberger DR, Egan MF, Bertolino A, Callicott JH, Mattay VS, Lipska BK, Berman KF, Goldberg TE (2001) Neurobiology of schizophrenia and the role of atypical antipsychotics. Biol Psychiatry 50:825–844

    Article  PubMed  CAS  Google Scholar 

  • Wykes T, Reeder C, Corner J, Williams C, Everitt B (1999) The effects of neurocognitive remediation on executive processing in patients with schizophrenia. Schizophrenia Bulletin 25(2):291–307

    Article  PubMed  CAS  Google Scholar 

  • Wykes T, Reeder C, Williams C et al (2002) Are the effects of cognitive remediation ther-apy (CRT) durable? Results from an exploratory trial. Schizophrenia Res (in press)

    Google Scholar 

  • Yung A, Phillips LJ, McGorry PD et al (1998) A step towards indicated prevention ofschizophrenia. British Journal of Psychiatry 172 (Suppl 33):14–20

    CAS  Google Scholar 

  • Sensky T, Turkington T, Kingdon D, Scott JL, Scott J, Siddle R, O’Carroll M, Barnes TRE (2000) A randomised, controlled trial of cognitive behaviour therapy for persistent positive symptoms in schizophrenia resistant to medication. Archives of General Psychiatry 57:165–173

    Article  PubMed  CAS  Google Scholar 

  • Young DA, Zakzanis KK, Bailey C, Davila R, Griese J, Sartory G, Thom A (1998) Further parameters of insight and neuropsychological deficit in schizophrenia and other chronic mental disease. J New Ment Dis 186(1):44–50

    Article  CAS  Google Scholar 

  • Yung A, Phillips LJ, McGorry PD et al (1998) A step towards indicated prevention of schizophrenia. British Journal of Psychiatry 172 (Suppl 33):14–20

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. School of Psychiatry and Behavioural Sciences, University of Manchester, Wythenshawe Hospital, Manchester, UK

    Shôn W. Lewis & Richard J. Drake

Authors
  1. Shôn W. Lewis
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Richard J. Drake
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department and Institute of Psychiatry - Faculty of Medicine, University of São Paulo, 3671, 05403-010, São Paulo - SP, Brazil

    Wagner F. Gattaz M.D. (Full Professor of Psychiatry & Director of the Laboratory of Neuroscience) (Full Professor of Psychiatry & Director of the Laboratory of Neuroscience)

  2. University of Heidelberg, 122120, 68072, Mannheim, Germany

    Heinz Häfner (Prof.em.of Psychiatry, Director em., Head) (Prof.em.of Psychiatry, Director em., Head)

  3. Central Institute of Mental Health, 122120, 68072, Mannheim, Germany

    Heinz Häfner (Prof.em.of Psychiatry, Director em., Head) (Prof.em.of Psychiatry, Director em., Head)

  4. Schizophrenia Research Unit, 122120, 68072, Mannheim, Germany

    Heinz Häfner (Prof.em.of Psychiatry, Director em., Head) (Prof.em.of Psychiatry, Director em., Head)

Rights and permissions

Reprints and permissions

Copyright information

© 2004 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Lewis, S.W., Drake, R.J. (2004). What can psychological treatments say about causes in schizophrenia?. In: Gattaz, W.F., Häfner, H. (eds) Search for the Causes of Schizophrenia. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-7985-1953-4_27

Download citation

  • DOI: https://doi.org/10.1007/978-3-7985-1953-4_27

  • Publisher Name: Steinkopff, Heidelberg

  • Print ISBN: 978-3-642-62331-8

  • Online ISBN: 978-3-7985-1953-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation