Abstract
Auditory hallucinations are a central feature of schizophrenia and a source of distress and disability for many patients. Although often responsive to treatment, in about a third of patients they are resistant to treatment or only partially improve (Shergill et al. 1999). In patients with schizophrenia auditory hallucinations of speech (auditory verbal hallucinations) are the most common type, and these usually involve derogatory phrases addressed to the patient in the second person (Junginger and Frame 1985).
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References
Aleman A, Bocker KB, Hijman R, de Haan EH, Kahn RS (2003a) Cognitive basis of hallucinations in schizophrenia: role of top-down information processing. Schizophrenia Research 1926:1–11
Aleman A, Koen A, Böcker B, Hijman R, de Haan E, Kahn R (2003) Cognitive basis of hallucinations in schizophrenia: role of top-down information processing. Schizophrenia Research 64:175–185
Allen P, Johns L, Fu C, Broome M, Brammer M, Vythelingum N, McGuire PK (2004) Misattribution of external speech in patients with delusions and hallucinations. Schizophrenia Research (in press)
Barta PE, Pearlson GD, Powers RE et al (1990) Auditory hallucinations and smaller superior temporal gyral volume in schizophrenia. American Journal of Psychiatry 39:784–788
Bentall RP, Slade PD (1985) Reality testing and auditory hallucinations: a signal detection analysis. British Journal of Clinical Psychology 24:159–169
Blakemore SJ, Wolpert DM, Frith CD (2002) Abnormalities in the awareness of action. Trends in Cognitive Sciences 6:237–242
Cahill C, Silbersweig D, Frith C (1996) Psychotic experiences induced in deluded pa-tients using distorted auditory feedback. Cognitive Neuropsychiatry 1:201–211
Cleghorn JM, Franco S, Szechtman B et al (1992) Towards a brain map of auditory hallucinations. American Journal of Psychiatry 149:1062–1069
Chua S, Wright I, Murray RM, Friston KJ, Liddle PF, McGuire PK (1997) Grey matter correlates of syndromes in schizophrenia: a semi-automated analysis of structural magnetic resonance images. British Journal of Psychiatry 170:406–410
DeLisi L, Hoff AL, Neale C, Kushner M (1994) Asymmetries in the superior temporal lobe in male and female first-episode schizophrenic patients: measures of the planum temporale and superior temporal gyrus by MRI. Schizophrenia Research 12:19–28
Dierks T, Linden DEJ, Jandl M, Formisano E, Goebel R, Lanfermann H, Singer W (1999) Activation of Heschl’s gyrus during auditory hallucinations. Neuron 22:615–621
Evans C, McGuire PK, David A (2000) Is auditory imagery defective in patients with auditory hallucinations? Psychological Medicine 30(1):137–148
Farah M J, Smith AF (1983) Perceptual interference and facilitation with auditory imagery. Perceptiion & Psychophysics 33(5):475–478
Frith CD, Done DJ (1987) Towards a neuropsychology of schizophrenia. British Journal of Psychiatry 153:437–443
Frith CD (1992) The Cognitive Neuropsychology of Schizophrenia. Erlbaum, Taylor & Francis, Hove, UK
Fu C, Vythelingum N, Andrew C, Brammer M, Amaro Jr E, Williams S, McGuire PK (2001) Alien voices… who said that? Neural correlates of impaired verbal self-monitoring in schizophrenia. Neuroimage 13:1052
Garety PA, Kuipers E, Fowler D, Freeman D, Bebbington PE (2001) A cognitive model of the positive symptoms of psychosis. Psychological Medicine 31:189–195
Hoffman RE, Hawkins KA, Gueorguieva R, Boutros NN, Rachid F, Carroll K, Krystal JH (2003) Transcranial magnetic stimulation of left temporoparietal cortex and medication-resistant auditory hallucinations. Archives of General Psychiatry 60(1): 49–56
Johns L, McGuire PK (1999) Verbal self-monitoring and auditory hallucinations in schizophrenia. Lancet 353:469–470
Johns L, Rossell S, Ahmad F, Frith C, Hemsley D, Kuipers L, McGuire PK (2001) Auditory verbal hallucinations and defective verbal self-monitoring in schizophrenia. Psychological Medicine 31:705–715
Junginger J, Frame CL (1985) Self-report of the frequency and phenomenology of verbal hallucinations. The Journal of Nervous & Mental Disease 173:149–155
Liddle PF, Friston KJ, Frith CD, Hirsch SR, Jones T, Frackowiak RSJ (1992) Patterns of cerebral blood flow in schizophrenia. British Journal of Psychiatry 160:179–186
McGuire PK, Syed GMS, Murray RM (1993) Increased blood flow in Broca’s area during auditory hallucinations in schizophrenia. Lancet 342:703–706
McGuire PK, Silbersweig DA, Wright I, Murray RM, David AS, Frackowiak R, Frith CD (1995) Abnormal perception of inner speech: a physiological basis for auditory hallucinations. Lancet 346:596–600
McGuire PK, Silbersweig DA, Frith CD (1996) Functional neuroanatomy of verbal self-monitoring. Brain 119:907–917
McGuire PK, Frith CD (1996) Disordered functional connectivity and schizophrenia. Psychological Medicine 26:663–667
Seal M, Aleman A, McGuire P (2004) Alluring imagery, unanticipated speech and deceptive memory: neurocognitive models of auditory verbal hallucinations in schizophrenia. Cognitive Neuropsychiatry 9:43–72
Shenton ME, Kikinis R, Jolesz FA, Pollack SD, LeMay M, Wible CG, Hokama H, Martin J, Metcalf D, Coleman M, McCarley RW (1992) Abnormalities of the left temporal lobe and thought disorder in schizophrenia. A quantitative magnetic resonance imaging study. New England Journal of Medicine 327:604–612
Shergill S, Murray RM, McGuire PK (1998) Auditory hallucinations: a review of psychological treatments. Schizophrenia Research 32:137–150
Shergill S, Bullmore E, Williams S, Brammer M, Murray RM, McGuire PK (2000) Functional anatomy of auditory verbal imagery in patients with auditory verbal hallucinations. American Journal of Psychiatry 157:1691–1693
Shergill S, Brammer M, Williams S, Murray RM, McGuire PK (2000) Mapping auditory hallucinations in schizophrenia using functional magnetic resonance imaging. Archives of General Psychiatry 57:1033–1038
Shergill S, Cameron L, Brammer M, Williams S, Murray RM, McGuire PK (2002) Modality-specif neural correlates of auditory and somatic hallucinations. Journal of Neurology, Neurosurgery & Psychiatry 71:688–690
Shergill S, Fukuda R, Brammer M, Murray RM, McGuire PK (2002) Modulation of temporal cortical activity during generation of inner speech. Human Brain Mapping 16:219–227
Shergill S, Fukuda R, Brammer M, Murray RM, McGuire PK (2003) Impaired monitoring of inner speech in schizophrenia. British Journal of Psychiatry 182:525–531
Vita A, Dieci M, Giobbio GM, Caputo A, Ghiringhelli M, Garbarini M, Medini AP, Morganti C, Tenconi F, Cesana B, Invernizzi G (1995) Language and thought disorder in schizophrenia: brain morphological correlates. Schizophrenia Research 15:243–251
Vita A, Dieci M, Giobbio GM, Caputo A, Ghiringhelli M, Garbarini M, Medini AP, Morganti C, Tenconi F, Cesana B, Invernizzi G (1995) Language and thought disorder in schizophrenia: brain morphological correlates. Schizophrenia Research 15:243–251
Wright IC, McGuire PK, Poline J-B, Travere JM, Murray RM, Frackowiak RSJ, Friston KJ (1995) A voxel-based method for the statistical analysis of grey and white matter density applied to schizophrenia. Neuroimage 2:244–252
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© 2004 Springer-Verlag Berlin Heidelberg
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McGuire, P. (2004). Neuroimaging studies of auditory verbal hallucinations. In: Gattaz, W.F., Häfner, H. (eds) Search for the Causes of Schizophrenia. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-7985-1953-4_13
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DOI: https://doi.org/10.1007/978-3-7985-1953-4_13
Publisher Name: Steinkopff, Heidelberg
Print ISBN: 978-3-642-62331-8
Online ISBN: 978-3-7985-1953-4
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