Melanoma Arising in Blue Nevus

  • Guido Massi
  • Philip E. Leboit


Melanoma can develop in a blue nevus. The blue nevus is generally a “cellular” variant (common and cellular are oversimplifications, as there are many more patterns of blue nevus than these), but there are a few recorded cases of malignant change in sparsely cellular dermal melanocytoses such as Ota nevus. In order to make a diagnosis of melanoma arising in a blue nevus, the basic histological characteristics of the latter must be recognizable at the periphery of the lesion, or (less satisfactory) a previous biopsy should unequivocally show a benign blue nevus.


Previous Biopsy Blue Nevus Brisk Mitotic Activity Peculiar Variant Cellular Blue Nevus 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • Guido Massi
    • 1
  • Philip E. Leboit
    • 2
  1. 1.Department of PathologyCatholic University Medical SchoolRomeItaly
  2. 2.University of CaliforniaSan FranciscoUSA

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