Melanoma with Neural Differentiation

  • Guido Massi
  • Philip E. Leboit


Melanoma with neural differentiation is a peculiar form of spindle cell melanoma, closely related to desmoplastic melanoma and neurotropic melanoma. The particular characteristic of this entity is its histological similarity with malignant peripheral nerve sheath tumor (neurofibrosarcoma). The term is best applied to lesions in which neural differentiation is the predominant finding. Alternative terms are neural transforming melanoma, neural or neuroid melanoma, and melanoma with neural metaplasia.


Neural Differentiation Malignant Peripheral Nerve Sheath Tumor Amelanotic Malignant Melanoma Malignant Schwannoma Desmoplastic Melanoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • Guido Massi
    • 1
  • Philip E. Leboit
    • 2
  1. 1.Department of PathologyCatholic University Medical SchoolRomeItaly
  2. 2.University of CaliforniaSan FranciscoUSA

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