Nevi on Genital Skin

  • Guido Massi
  • Philip E. Leboit


The majority of nevi situated on genital skin (and on other hormonally-affected skin regions) has no peculiar histological characteristics (or have the architectural features of a Clark or dysplastic nevus). This is especially true in post-menopausal women. A few of them, especially in younger women show important cytological and structural findings that can simulate melanoma, leading to inappropriate resection in areas in which conservation of tissue is especially important (Friedman). Nevi on the vulva are much better described than are nevi on male genitalia. This is probably due to the different ages at which genitalia are examined by doctors. Young women are subject to examination at routine gynecologic visits and by obstetricians, while the genitalia of men are not usually scrutinized until they visit urologists in late middle age (at which point many of their nevi have faded).


Male Genitalia Dysplastic Nevus Blue Nevus Genital Skin Dermal Component 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. Bart RS, Kopf AW. Tumor conference #45. Congenital nevocytic nevus of penis and scrotum. J Dermatol Surg Oncol. 1982 Dec;8(12):1020–1021.PubMedGoogle Scholar
  2. Clark WH Jr, Hood AF, Tucker MA, Jampel RM. Atypical melanocytic nevi of the genital type with a discussion of reciprocal parenchymal-stromal interactions in the biology of neoplasia. Hum Pathol. 1998 Jan;29(1 Suppl 1):S1–24.PubMedCrossRefGoogle Scholar
  3. Christensen WN, Friedman KJ, Woodruff JD, Hood AF. Histological characteristics of vulvar nevocellular nevi. J Cutaneous Path 1987 14(2):87–91.CrossRefGoogle Scholar
  4. Friedman RJ, Ackerman AB. Difficulties in the histologic diagnosis of melanocytic nevi on the vulvae of premenopausal women. In: Ackerman AB ed. Pathology of Malignant Melanoma. Masson, New York, 1981; 119–127Google Scholar
  5. Heim K, Hopfl R, Muller-Holzner E, Bergant A, Dapunt O. Multiple blue nevi of the vagina. A case report. J Reprod Med. 2000 Jan;45(1):42–44.PubMedGoogle Scholar
  6. Rongioletti F, Ball RA, Marcus R, Barnhill RL. Histopathological features of flexural melanocytic nevi: a study of 40 cases. J Cutan Pathol. 2000 May;27(5):215–217.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • Guido Massi
    • 1
  • Philip E. Leboit
    • 2
  1. 1.Department of PathologyCatholic University Medical SchoolRomeItaly
  2. 2.University of CaliforniaSan FranciscoUSA

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