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Deep Penetrating Nevus

  • Guido Massi
  • Philip E. Leboit

Abstract

The deep penetrating nevus is an intradermal or sometimes compound melanocytic neoplasm with three distinctive histological characteristics: — it occupies a large part of the dermis, occasionally reaching the subcutis; — it contains large cells with pale cytoplasm and a variably sized nucleus; — and it has a dark color on clinical examination due to its many melanophages. Its pigmentation, periadnexal pattern and equal size of cells at the top and base of the lesion are findings that suggest that it is a variant of blue nevus.

Keywords

Metastatic Melanoma Atypical Cell Blue Nevus Pale Cytoplasm Junctional Component 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • Guido Massi
    • 1
  • Philip E. Leboit
    • 2
  1. 1.Department of PathologyCatholic University Medical SchoolRomeItaly
  2. 2.University of CaliforniaSan FranciscoUSA

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