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Abstract

The deep penetrating nevus is an intradermal or sometimes compound melanocytic neoplasm with three distinctive histological characteristics: — it occupies a large part of the dermis, occasionally reaching the subcutis; — it contains large cells with pale cytoplasm and a variably sized nucleus; — and it has a dark color on clinical examination due to its many melanophages. Its pigmentation, periadnexal pattern and equal size of cells at the top and base of the lesion are findings that suggest that it is a variant of blue nevus.

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References

  • Barnhill RL. Pathology and prognostic factors. Curr Opin Oncol. 1993 Mar;5(2):364–376.

    Article  PubMed  CAS  Google Scholar 

  • Cooper PH. Deep penetrating (plexiform spindle cell) nevus. A frequent participant in combined nevus. J Cutan Pathol. 1992 Jun;19(3):172–180.

    Article  PubMed  CAS  Google Scholar 

  • Elder E.D, Murphy G.F. Atlas of tumor pathology. Melanocytic tumor of the skin. AFIP 1991 Washington, page 31.

    Google Scholar 

  • Mehregan DA, Mehregan AH. Deep penetrating nevus. Arch Dermatol. 1993 Mar;129(3):328–331.

    Article  PubMed  CAS  Google Scholar 

  • Mehregan DR, Mehregan DA, Mehregan AH. Proliferating cell nuclear antigen staining in deep-penetrating nevi. J Am Acad Dermatol. 1995 Oct;33(4):685–687.

    Article  PubMed  CAS  Google Scholar 

  • Seab JA Jr, Graham JH, Helwig EB. Deep penetrating nevus. Am J Surg Pathol. 1989 Jan;13(1):39–44.

    Article  PubMed  Google Scholar 

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© 2004 Springer-Verlag Berlin Heidelberg

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Massi, G., Leboit, P.E. (2004). Deep Penetrating Nevus. In: Histological Diagnosis of Nevi and Melanoma. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-7985-1943-5_14

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  • DOI: https://doi.org/10.1007/978-3-7985-1943-5_14

  • Publisher Name: Steinkopff, Heidelberg

  • Print ISBN: 978-3-642-62222-9

  • Online ISBN: 978-3-7985-1943-5

  • eBook Packages: Springer Book Archive

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