Deep Penetrating Nevus
The deep penetrating nevus is an intradermal or sometimes compound melanocytic neoplasm with three distinctive histological characteristics: — it occupies a large part of the dermis, occasionally reaching the subcutis; — it contains large cells with pale cytoplasm and a variably sized nucleus; — and it has a dark color on clinical examination due to its many melanophages. Its pigmentation, periadnexal pattern and equal size of cells at the top and base of the lesion are findings that suggest that it is a variant of blue nevus.
KeywordsMetastatic Melanoma Atypical Cell Blue Nevus Pale Cytoplasm Junctional Component
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- Elder E.D, Murphy G.F. Atlas of tumor pathology. Melanocytic tumor of the skin. AFIP 1991 Washington, page 31.Google Scholar